Abstract: Methods for making glasses and glass-ceramics comprising Al2O3 and SiO2. Glasses made according to the present invention can be made, formed as, or converted into glass beads, articles (e.g., plates), fibers, particles, and thin coatings. Some embodiments of glass-ceramic particles made according to the present invention can be are particularly useful as abrasive particles.

Abstract: A dental material delivery system includes an applicator having a proximal segment, a median bending segment and a tip; an elongated handle; and a cap. The proximal segment of the applicator is nonremovably frictionally mounted within a proximal bore section of the handle, the median bending segment of the applicator is aligned generally longitudinally with an annular weakened wall line of the handle, and the tip of the applicator extends into a distal bore section of the handle. A quantity of dental material is disposed within the distal section of the handle. The cap is mounted to the handle adjacent the distal end of the handle to seal the handle. The wall of the handle is separable at the annular weakened wall line to permit withdrawal of the applicator tip and transfer of the dental material to a surface.

Abstract: Aryl substituted imidazoquinoline compounds, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.

Abstract: A polarizer is used with a liquid crystal display (LCD) cell whose liquid crystal molecules are switched in the plane of the cell. The LCD has birefringent properties that are different from other types of LCD cell and, unlike other types of LCD, the image contrast is maintained and there is little color shift in the dark state when a low birefringence polarizer is used with the SIP LCD cell. In one embodiment, the x-z retardation of the layers between the polarization-sensitive absorbing layer and the LCD is less than 20 nm. In another embodiment, the x-z birefringence is less than 0.0005. The low levels of retardation and birefringence may be achieved by omitting the commonly used cellulose triacetate layer between the polarization-sensitive absorbing layer and the LCD.

Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and urea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and aryl or alkenyl functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract: Disclosed is a touch screen calibration system and method that applies a signal to a the terminals of a touch screen and applies a calibration impedance to those terminals; the effect of the calibration impedance applied to the terminals is sensed; the X, Y position for each terminal is calculated upon application of the calibration impedance and the offset error for each terminal is calculated and applied to obtain the corrected touch position for a measured touch position; in addition the gain error may be calculated for each terminal and applied to obtain the corrected touch position.

Abstract: The present invention provides reflective films and other optical bodies which exhibit sharp bandedges on one or both sides of the main reflection bands. The optical bodies comprise multilayer stacks M1 and M2, each having first order reflections in a desired part of the spectrum and comprising optical repeating units R1 and R2, respectively. At least one of the optical repeating units R1 and R2 varies monotonically in optical thickness along the thickness of the associated multilayer stack.

Abstract: The present invention provides a dental material that includes a hardenable resin system and a first initiator system capable of hardening the hardenable resin.

Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and aryl or alkenyl functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.

Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

Abstract: Dye labeled imidazonaphthyridine, imidazopyridine and imidazoquinoline compounds having immune response modulating activity are disclosed. The compounds arc useful, inter alia, for determining the binding and/or receptor sites of the molecules.

Abstract: Disclosed are block copolymers and end-functionalized polymers containing in their backbones at least one fluoro alkyl (meth)acrylate mer unit comprising —C6F13, —C4F9, or —C3F7.

Abstract: A transdermal delivery device including at least one pressure sensitive adhesive layer having a first major surface and a second major surface, wherein at least one of the first and second major surfaces is a structured surface; a cap layer in contact with the structured surface of an adhesive layer; and, at least one medicinal ingredient between the adhesive layer and the cap layer.

Abstract: A polycrystalline translucent aluminum oxide ceramic material having an average grain size of no greater than 1.0 micron and a Contrast Ratio value of less than about 0.7. The material can be in the form of a dental mill blank, dental prosthesis or other dental article or non-dental article.

Abstract: The application discloses methods of plasma treatment that employ an ion sheath in a capacitively-coupled system to increase the hydrophilicity of porous articles, including microporous articles having pore sizes of 0.05 to 1.5 micrometers, both on their surfaces and in their pores such that the articles' bulk wetting properties are improved.

Abstract: The invention relates to inducing a refractive index change in the glass substrate of a polymer coated optical device by using a high numeric aperture lens to focus a femtosecond laser beam through the polymeric coating to the substrate without damaging the polymeric coating.