Patents Assigned to 3ST Research LLC
  • Methods and compositions for preventing opioid abuse
    Patent number: 11020386
    Abstract: Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: June 1, 2021
    Assignees: ALBANY MOLECULAR RESEARCH, INC., 3ST RESEARCH LLC
    Inventors: Matthew Surman, Kathryn Golden, Paolo Pasetto, Xiaomin Jin, Xiaowu Jiang, Fatoumata Camara, John K. Thottathil
  • Methods and compositions for preventing opioid abuse
    Patent number: 10695342
    Abstract: Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: June 30, 2020
    Assignees: ALBANY MOLECULAR RESEARCH, INC., 3ST RESEARCH LLC
    Inventors: Matthew Surman, John K. Thottathil, Kathryn Golden, Paolo Pasetto, Xiaomin Jin, Xiaowu Jiang, Fatoumata Camara
  • Alpha-hydroxy carboxylic acid and derivatives and other GRAS based prodrugs of oxycodone and uses thereof
    Patent number: 10696683
    Abstract: The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxycodone, in a manner that substantially decreases or deters the potential for opioid abuse, addiction, illicit and illegal use, and overdose. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: June 30, 2020
    Assignee: 3ST Research LLC
    Inventor: John K. Thottathil
  • Methods and compositions for preventing opioid abuse
    Patent number: 10226456
    Abstract: Abuse-resistant opioid compounds, drug delivery systems, pharmaceutical compositions comprising an opioid covalently bound to a chemical moiety are provided. Methods of delivering an active ingredient to a subject and methods of preventing opioid abuse are also provided.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: March 12, 2019
    Assignee: 3ST Research LLC
    Inventor: John K. Thottathil
  • Alpha-hydroxy carboxylic acid and derivatives and other GRAS based prodrugs of oxycodone and uses thereof
    Patent number: 10017519
    Abstract: The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxycodone, in a manner that substantially decreases or deters the potential for opioid abuse, addiction, illicit and illegal use, and overdose. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.
    Type: Grant
    Filed: November 29, 2015
    Date of Patent: July 10, 2018
    Assignee: 3ST Research LLC
    Inventor: John K. Thottathil
  • Alpha-hydroxy carboxylic acid and derivatives and other GRAS-based prodrugs of oxymorphone and uses thereof
    Patent number: 9987269
    Abstract: The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to the opioid oxymorphone, in a manner that substantially decreases or deters the potential for opioid abuse, addiction, illicit and illegal use, and overdose. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: June 5, 2018
    Assignee: 3ST Research LLC
    Inventor: John K. Thottathil