Abstract: Provided herein are compositions that includes AAVs and AAV vectors that include a sequence encoding a SARS-CoV-2 polypeptide or a fragment thereof. Also provided herein are methods and materials for making and using AAVs and AAV vectors to generate immunity to a coronavirus in a subject.
Type:
Application
Filed:
April 9, 2021
Publication date:
May 11, 2023
Applicants:
4MVac LLC, Trustees of the University of Pennsylvania, Johnson & Johnson, Inc.
Inventors:
Hansell Hall Stedman, Geoffrey Tabin, Charles R. Bridges