Abstract: Provided is a system and method for automated patient interaction. The method includes parsing a patient complaint comprising a plurality of words, determining a subset of patient queries from a plurality of patient queries based on the patient complaint and patient data, communicating the subset of patient queries to a first computing device; receiving, from the first computing device, responses to at least a portion of the subset of patient queries; generating output data based on the subset of patient queries and the responses; communicating the output data to a second computing device; receiving, from the second computing device, a user input corresponding to at least one patient query of the subset of patient queries; and training, based on the user input, at least one machine-learning algorithm configured to output at least one patient query based on at least one of the patient complaint and a subsequent patient complaint.