Abstract: This invention relates to new derivatives of 4-amino-3-sulfonamido-pyridine having diuretic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which R.sub.1 represents hydrogen or an alkyl, cycloalkyl, carbamoyl or sulfonamido radical;R.sub.2 represents an alkyl, halogenoalkyl, cycloalkyl, alkenyl, alkynyl, hydroxyalkyl, alkoxyalkyl, phenyl (possibly substituted), phenylalkyl, diphenylmethyl, isobornyl, furfuryl, tetrahydrofurfuryl, dialkylaminoalkyl or heterocyclic radical; or R.sub.1 and R.sub.2 form together with the nitrogen atom a saturated heterocyclic radical; andX represents an alkoxy radical, an heterocyclic amino radical, or a secondary or tertiary amino radical having its first substituent selected from hydrogen and the alkyl and alkenyl groups, and its second substituent selected from the alkyl, alkenyl, alkynyl, hydroxyalkyl, diphenylmethyl, isorbornyl, furfuryl, tetrahydrofurfuryl, phenylalkyl and heterocyclic groups.

Abstract: This invention relates to new derivatives of 1,3-benzodioxole, namely 2-[N-(R.sub.1, R.sub.2 aminocarbamoyl)]-phenylaminomethyl-1,3-benzodioxole, in which R.sub.1 is hydrogen or a lower alkyl group, R.sub.2 is a lower alkyl group and R.sub.1 and R.sub.2 may also form with the attached nitrogen atom a nitrogenous heterocyclic ring.The new derivatives of 1,3-benzodioxole are valuable therapeutic agents for the treatment of heart arrhythmy.

Abstract: This invention relates to new derivatives of pyridine having hypo-uricemic or hypolipemic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an oxy or thio group, R.sub.1 represents hydrogen, a group of the formula R.sub.3 NHCO (II), wherein R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, cycloalkyl or possibly substituted phenyl group, or a group of the formula R.sub.4 --CO (III) in which R.sub.4 represents a C.sub.1- C.sub.4 -alkyl group or a possibly substituted phenyl group, and R', R" and R'" represent each a possible substituent selected from the group comprising the halogens, the trifluoromethyl and the C.sub.1- C.sub.4 alkyl groups.

Abstract: This invention relates to new derivatives of 1,2,4-thiadiazine having anti-inflammatory properties.The new derivatives of 1,2,4-thiadiazine may be represented by the following general formula: ##STR1## in which R.sub.1 and Z each represent an unsubstituted or substituted phenyl group.This invention relates also to the N-oxides of the compounds of formula I, as well as to the acid and base addition salts of said compounds.

Abstract: This invention relates to new derivatives of pyridine having anti-inflammatory and diuretic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an amino, C.sub.1 -C.sub.4 -alkylamino, oxy or thio group, R.sub.1 represents a group of the formula R.sub.3 NHCA (II), wherein A represents oxygen or sulfur, and R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, alkenyl, cycloalkyl, phenyl (which may be substituted) or R.sub.4 CO (III) group, R.sub.4 representing a phenyl group (which may be substituted), R.sub.2 represents hydrogen or a C.sub.1 -C.sub.4 alkyl group and Z represents a C.sub.1 -C.sub.4 -alkyl, methylfuryl, pyridyl or phenyl group (which may be substituted).This invention relates also to the N-oxides of the compounds of formula I, as well as to the acid and base addition salts of said compounds.

Abstract: This invention relates to new derivatives of 1,3-benzodioxole, namely 2-[N-(R.sub.1, R.sub.2 amino-alkyl or alkanoyl or carbamoyl)]-phenylaminomethyl-1,3-benzodioxole, in which R.sub.1 is hydrogen or a lower alkyl group, R.sub.2 is a lower alkyl group and R.sub.1 and R.sub.2 may also form with the attached nitrogen atom a nitrogenous heterocyclic ring.The new derivatives of 1,3-benzodioxole are valuable therapeutic agents for the treatment of heart arrhythmy.

Abstract: This invention relates to compounds of the formula: ##STR1## wherein R.sub.1 in the 3- or 5-position is a carboxamido group whereas R.sub.2 in the 2-position is a 1-methyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.

Abstract: This invention relates to compounds of the formula: ##SPC1##Wherein R.sub.1 in the 3- or 5-position is preferably a substituted sulfonamido or a carboxamido group whereas R.sub.2 in the 2-, 4- or 6-position is preferably an alkyl- or hydroxyalkyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.

Abstract: This invention relates to new derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene), namely 2-[N-phenyl-N-(R.sub.1,R.sub.2 -aminoalkyl or alkanoyl)]-amino-(1,2,3,4-tetrahydronaphthalenes), in which R.sub.1 and R.sub.2 represent a lower alkyl group or form together with the attached nitrogen atom a nitrogenous heterocyclic ring, with the proviso that R.sub.1 may also represent hydrogen, as well as to the acid addition salts of these new derivatives.These new derivatives are active for the treatment of heart arrhythmy.

Abstract: This invention relates to new derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene), namely 2-[N-phenyl-N-(R.sub.1,R.sub.2 -aminoalkyl or alkanoyl)]-amino-(1,2,3,4-tetrahydronaphthalenes), in which R.sub.1 and R.sub.2 represent a lower alkyl group or form together with the attached nitrogen atom a nitrogenous heterocyclic ring, with the proviso that R.sub.1 may also represent hydrogen, as well as to the acid addition salts of these new derivatives.These new derivatives are active for the treatment of heart arrhythmy.

Abstract: This invention relates to compounds of the formula ##SPC1##Wherein R.sub.1 in the 3- or 5-position is a cyano group whereas R.sub.2 and in the 2-position is a N-methyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.

Abstract: New 2-R-amino-tetraline-1-ones, in which R represents a pyridyl or phenyl radical which may be substituted by a methoxy group are prepared by reacting 2-bromo-tetralone with an amine of the formula R-NH.sub.2.These new 2-R-amino-tetraline-1-ones are valuable intermediates for the preparation of pharmaceutically active compounds.

Abstract: This invention relates to new derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene), namely 2-[N-phenyl-N-(R.sub.1,R.sub.2 -aminoalkyl or alkanoyl)]-amino-(1,2,3,4-tetrahydronaphthalenes), in which R.sub.1 and R.sub.2 represent a lower alkyl group or form together with the attached nitrogen atom a nitrogenous heterocyclic ring, with the proviso that R.sub.1 may also represent hydrogen, as well as to the acid addition salts of these new derivatives.These new derivatives are active for the treatment of heart arrhythmy.

Abstract: This invention relates to new derivatives of pyridine having anti-inflammatory and diuretic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an amino, C.sub.1 -C.sub.4 -alkylamino, oxy or thio group, R.sub.1 represents a group of the formula R.sub.3 NHCA (II), wherein A represents oxygen or sulfur, and R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, alkenyl, cycloalkyl, phenyl (which may be substituted) or R.sub.4 CO (III) group, R.sub.4 representing a phenyl group (which may be substituted), R.sub.2 represents hydrogen or a C.sub.1 -C.sub.4 alkyl group and Z represents a C.sub.1 -C.sub.4 -alkyl, methylfuryl, pyridyl or phenyl group (which may be substituted).This invention relates also to the N-oxides of the compounds of formula I, as well as to the acid and base addition salts of said compounds.