Patents Assigned to A. H. Robbins Company, Inc.
  • Anxiolytic-n-(1-azabicyclo(2.2.2)oct-3-yl) benzamides and thiobenzamides
    Patent number: 4908370
    Abstract: Compounds of general formula I: ##STR1## wherein: X represents oxygen or sulphur;R.sup.1 represents loweralkyl;R.sup.2 represents hydrogen, halo, 4,5-benzo, loweralkoxy, amino, methylamino or dimethylamino;R.sup.3 represents hydrogen or loweralkyl; andn is 1 or 2and their pharmaceutically acceptable acid addition salts have anxiolytic activity. In particular, they have activity against anxiety induced by the withdrawal from ingested substances such as narcotics (e.g. cocaine), alcohol and nicotine.
    Type: Grant
    Filed: December 15, 1987
    Date of Patent: March 13, 1990
    Assignee: A. H. Robbins Company, Inc.
    Inventors: Robert J. Naylor, Brenda Naylor