Abstract: The invention relates to a device for applying a plurality of microdroplets to a substrate (65) comprising a plate (50) provided with a plurality of bore holes (51) and a bottom (52) which is connected to said plate (50), and is provided with a plurality of channels (53). The device is characterized in that each bore (51) of the plate (50) is assigned to a single channel (53) of the bottom (52). The invention also relates to a method for producing this device, the use of this device for applying a plurality of microdroplets to a substrate (65), as well as a method for applying a plurality of microdroplets to a substrate (65).