Abstract: Disclosed is an adjuvant for improving the bioavailability of bioactive compositions. The adjuvant is prepared from a byproduct of mint flavor production. In vitro and in vivo testing confirms effectiveness. The adjuvant contains a mixture of compounds which is effective to improve the oral bioavailability of a bioactive composition normally having limited absorptivity, and it comprises a mixture of nonpolar compounds and compounds with some polar characteristics. In preferred form the nonpolar compounds comprise compounds selected from a group that includes terpene hydrocarbons and terpene derivatives and the compounds with some polar characteristics comprise compounds selected from a group that includes aldehydes, alcohols and ketones. The preferred compositions will have a ratio of nonpolar compounds and compounds with some polar characteristics is within the range of from 5:1 to 20:1. The adjuvants can enhance delivery of CoQ10 and other bioactive compositions, such as carotenoids (e.g.
Type:
Grant
Filed:
October 28, 2009
Date of Patent:
May 21, 2013
Assignee:
A. M. Todd Company
Inventors:
John Westcott Finley, John Weldon Finley, Igor Mezine, James M. Kehrer, II, Robert J. Justice, II
Abstract: Disclosed is an adjuvant for improving the bioavailability of bioactive compositions. The adjuvant is prepared from a byproduct of mint flavor production. In vitro and in vivo testing confirms effectiveness. The adjuvant contains a mixture of compounds which is effective to improve the oral bioavailability of a bioactive composition normally having limited absorptivity, and it comprises a mixture of nonpolar compounds and compounds with some polar characteristics. In preferred form the nonpolar compounds comprise compounds selected from a group that includes terpene hydrocarbons and terpene derivatives and the compounds with some polar characteristics comprise compounds selected from a group that includes aldehydes, alcohols and ketones. The preferred compositions will have a ratio of nonpolar compounds and compounds with some polar characteristics is within the range of from 5:1 to 20:1. The adjuvants can enhance delivery of CoQ10 and other bioactive compositions, such as carotenoids (e.g.
Type:
Application
Filed:
October 28, 2009
Publication date:
August 5, 2010
Applicant:
A. M. TODD COMPANY
Inventors:
John Westcott Finley, John Weldon Finley, Igor Mezine, James M. Kehrer, II, Robert J. Justice, II
Abstract: The invention relates to water dispersible extract preparations derived from water soluble components of Labiatae family plant material, including plant material hay and previously extracted or spent hay, which possesses beneficial oral care properties, methods of their manufacturing and application of the preparations in oral care products.
Type:
Grant
Filed:
January 18, 2006
Date of Patent:
April 14, 2009
Assignee:
A.M. Todd Company
Inventors:
Igor Mezine, Huizhen Zhang, Mike Petteruti, Mary Opet, John Finley
Abstract: The invention relates to water dispersible extract preparations derived from water soluble components of Labiatae family plant material, including plant material hay and previously extracted or spent hay, which possesses beneficial oral care properties, methods of their manufacturing and application of the preparations in oral care products.
Type:
Application
Filed:
January 18, 2006
Publication date:
August 24, 2006
Applicant:
A.M. TODD COMPANY
Inventors:
Igor Mezine, Huizhen Zhang, Mike Petteruti, Mary Opet, John Finley
Abstract: Crystal-clear peppermint oil maintaining its noble character and having a reduced pulegone content, enhanced menthone and menthol content, and improved stability against menthofuran oxidation breakdown is produced by a stereospecific method of reduction by hydrogenation of pulegone in situ using a saturated aqueous solution of sodium sulfite in the presence of glacial acetic acid at approximately neutral pH.
Abstract: Crystal-clear peppermint oil maintaining its noble character and having a reduced pulegone content, enhanced menthone and menthol content, and improved stability against menthofuran oxidation breakdown is produced by a stereospecific method of reduction by hydrogenation of pulegone in situ using a saturated aqueous solution of sodium sulfite in the presence of glacial acetic acid at approximately neutral pH.
Abstract: A new and distinct peppermint plant ‘Clackamas’ characterized by its resistance to Mint rust (Puccinia menthe Pers), Mint wilt (Ferticillium dahliae and Verticillium albo-atrum), and Spider mites as well as a more upright growth habit and a lighter green color the Black Mitcham peppermint plant.
Abstract: A new and distinct peppermint plant ‘McKenzie’ characterized by its upright growth habit, vigorous and abundant root growth, resistance to Spider Mites (Tetranychus urticae), Mint rust (Puccinia menthe Pers), Mint wilt (Verticillium dahliae and Verticillium albo-atrum), and a distinct flower spike with mostly pinkish white petals and consistent oil quality throughout its phases of maturity.