Abstract: A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
Type:
Grant
Filed:
October 24, 2011
Date of Patent:
August 28, 2012
Assignee:
A.P. Pharma
Inventors:
Steven Y. Ng, Hui Rong Shen, Jorge Heller