Abstract: A container comprising a mouth the outside of said mouth comprising an external thread covering only part of the periphery of the mouth to provide at least one axially extending thread-free zone, a screw cap (2) for onscrewing onto the external thread, the skirt of the screw cap (2) comprising a hole (9) and means for preventing an unwanted unscrewing of the screw cap (2) said means consisting of an element (5) which is hinge-connected to the exterior side of the screw cap (2), said element can be swung over and be engaged with the free end of the screw cap, and said element has a projection (12) which extends through the hole (9) and ends in the thread-free zone when the screw cap (2) is in its closing position.

Abstract: Imidazole derivatives substituted in the 1-position by a carboxyalkyl group or an ester of a such and the acid addition salts thereof, and where possible the alkali metal and alkaline earth metal salts thereof possess good antiphlogistic and analgesic activities. Such compounds are prepared, for example, by introducing the carboxyalkyl group or an ester of a such into the 1-position of a corresponding imidazole derivative unsubstituted in the 1-position. Alternatively such compounds are prepared by reacting an appropriate keto-oxime with an appropriate amino compound and an appropriate aldehyde or acetal and optionally reducing the imidazole derivative thus obtained.