Abstract: The invention provides compositions and methods for metabolic health in an animal comprising administering a non-ketogenic composition to the animal, wherein the non-ketogenic composition comprises about 5% to about 25% carbohydrates, about 30% to about 60% protein, and about 10% to about 40% fat. Additionally, the composition can have a protein to carbohydrate ratio of at least 2:1.

Abstract: An articulated prosthesis, left in the patient's heart for repairing a tricuspid or mitral valve, is conceived so as to grip simultaneously all the three leaflets of the tricuspid valve, or the two of the mitral valve, so as to make them lay distended fully in the valve plane and assume a final configuration as in the common surgical procedure. It is also disclosed a related catching device and a device for repairing a tricuspid or mitral valve.

Abstract: A planar transistor device is disclosed including a gate structure positioned above a semiconductor substrate, the semiconductor substrate comprising a substantially planar upper surface, a channel region, a source region, a drain region, and at least one layer of a two-dimensional (2D) material that is positioned in at least one of the source region, the drain region or the channel region, wherein the layer of 2D material has a substantially planar upper surface, a substantially planar bottom surface and a substantially uniform vertical thickness across an entire length of the layer of 2D material in the gate length direction and across an entire width of the layer of 2D material in the gate width direction, wherein the substantially planar upper surface and the substantially planar bottom surface of the layer of 2D material are positioned approximately parallel to a substantially planar surface of the semiconductor substrate.

Abstract: A hydraulic fracking aqueous fluid, including: water; one or more soluble calcium salts; a carbonate ion generating compound; and one or more soluble zinc salts. A method for fracking an underground formation using the hydraulic fracking fluid.

Abstract: A valve extension tool is configured to operate a hand wheel of a valve. The valve extension tool includes a handle configured for operation by a first operator and a pipe assembly connected to the handle. The pipe assembly includes a proximal pipe segment connected to the handle, a crank connected to the proximal pipe segment and configured for operation by a second operator, and a distal pipe segment connected to the crank. In addition, the valve extension tool includes a front pipe segment connected to the distal pipe segment of the pipe assembly. Further, the valve extension tool includes a joint connected to the front pipe segment, wherein the joint is configured to engage a hand wheel of a valve.

Abstract: The present invention refers to new glycoconjugate antigens expressing built-in multiple epitopes and to polyvalent glycoconjugate vaccines intended for the protection of mammalians, and particularly for the protection of the human population from enteropathogenic bacteria, such as the Gram-positive anaerobic bacterium Clostridium difficile and the Gram-negative bacteria Salmonella typhi, Escherichia Coli, Vibrio Cholerae, Shigella flexneri, Salmonella typhimurium, Salmonella enteritidis, Salmonella paratyphi A, Shigella sonnei, Shigella dysenteriae, Salmonella cholerasuis, Klebsiella, Enterobacter, Pseudomonas aeruginosa and/or from viral gastrointestinal infections due to human noroviruses.

Abstract: A fitting agent for a hearing device and related method is disclosed, wherein the fitting agent is configured to initialize a user model comprising a user preference function; obtain a primary test setting for the hearing device; obtain a secondary test setting for the hearing device; present the primary test setting and the secondary test setting to a user; detect a user input of a preferred test setting indicative of a preference for either the primary test setting or the secondary test setting; and update the user model based on hearing device parameters of the preferred test setting, wherein to obtain the secondary test setting comprises: obtain a candidate set of candidate test settings; determine an uncertainty parameter for each candidate test setting; and select the secondary test setting from the candidate set of candidate test settings based on the uncertainty parameters of the candidate test settings.

Abstract: The present invention provides a method of assessing type 2 diabetes susceptibility and/or predicting treatment responsiveness in a human subject, the method comprising determining the identity of at least one allele at each of three or more positions of single nucleotide polymorphism (SNP) selected from the group consisting of: SLC16A11-rs75493593; HNF1A-rs483353044; TCF7L2-rs7903146; CDKN2A/B-rs10811661; CDKAL1-rs7756992; SLC30A8-rs3802177; IGF2BP2-rs4402960; FTO-rs9936385; PPARG-rs1801282; HHEX/IDE-rs1111875; ADCYS-rs11717195; JAZF1-rs849135; WSF1-rs4458523; INS-IGF2-rs149483638; KCNQ1-rs2237897; and KCNJ11-rs5219, and/or an SNP in linkage disequilibrium with any one of said SNPs at r2>0.8. Also provided are a genotyping tool and a type 2 diabetes risk assessment system for use in the method of the invention.

Abstract: Embodiments of the disclosure provide an optical antenna for a photonic integrated circuit (PIC). The optical antenna includes a vertically oriented semiconductor waveguide with a first end on a semiconductor layer. The vertically oriented semiconductor waveguide includes a first sidewall and a second sidewall opposite the first sidewall. A reflective material is along the second sidewall of the vertically oriented semiconductor waveguide. A first plurality of grating protrusions extends from the first sidewall of the vertically oriented semiconductor waveguide.

Abstract: A controllable Pitot device uses a Pitot nozzle supported by a Pitot nozzle holder for pumping fluid flowing in a first direction or in a second direction flowing opposite the first direction. The Pitot nozzle has one ingestion inlet pivotable to ingest fluid from either direction. Ingested fluid impinges on an obstacle interior to the Pitot nozzle which is disposed opposite the ingestion inlet to create a zone of fluid at stagnation pressure. Stagnation pressure pumps fluid via the interior of the Pitot nozzle through one of two openings for discharging pumped fluid out of a discharge outlet supported by the nozzle holder, to the exterior of the Pitot device. The nozzle holder can be a support structure or an embedded support operative with a rotating fluid machine.

Abstract: Method and system for optimizing the arrangement of a set of aircraft parts on a plate. The system includes a selection module which selects, from a set of data on the material of the set of parts and a set of geometric data associated with the set of parts, part grouping criteria including at least one optimized plate thickness value, an optimization module for optimizing the arrangement of the set of parts on a plate as a function of the part grouping criteria, cutting criteria and optimization criteria and a transmission module generating and transmitting, to a user system, optimization data representative of the optimization of the arrangement of the set of parts. The system makes it possible to take account of the parameters linked to the dimensions of the plate to optimize the arrangement of the set of parts.

Abstract: The X-ray emitting unit (100) comprises a box-shaped container (110) with a chamber inside it, and an X-ray tube located in the chamber; the box-shaped container (110) is provided with an opening (111) for X-rays and a plurality of openings for cooling and electrically insulating liquid; having: a first main opening (112A) for the inlet of cooling and electrically insulating liquid, a second main opening for the outlet of cooling and electrically insulating liquid; furthermore, the box-shaped container (110) has: at least one secondary opening (114A) of the first type for cooling and electrically insulating liquid and/or at least one secondary opening (116A, 116B) of the second type for cooling and electrically insulating liquid.

Abstract: A closure (8) with tamper-evident band (40) includes a fixed band (42, 142) and a movable body (50). The fixed band (42, 142), with tamper-evident band inviolate, is joined to the movable body (50) by a weakened portion (52, 152) The tamper-evident band (40) also includes a tamper-evident ring (70, 170) housed, with the tamper-evident band inviolate, in an inner compartment of the closure (8) to be hidden from view. The weakened portion (52, 152) tears due to the unscrewing of the closure (8) and the tamper-evident ring (70,170) pops out of the inner compartment and is arranged, with the seal violated, so as to separate a fixed edge (49, 149) of the fixed band (42, 142) from a movable edge (51, 151) of the movable body (50).

Abstract: A method detects a risk of collision between a motor vehicle and a secondary object located in traffic lanes adjacent to the main traffic lane of the vehicle, in the event of a lane change by the vehicle, which involves detecting objects in a predetermined danger zone, and estimating a time-to-collision between the vehicle and a detected object. Detecting objects in a danger zone involves: calculating the actual distance between the vehicle and each object detected by the radar, the actual distance corresponding to the length of an arc between two points; determining a danger zone as a function of lines of the main traffic lane and a width of the main traffic line; and checking, for each object detected by the radar, whether its coordinates are inside the predetermined danger zone.

Abstract: A control circuit includes: an output terminal configured to be coupled to a control terminal of a transistor that has a current path coupled to an inductor; a transconductance amplifier configured to produce a sense current based on a current flowing through the current path of the transistor; and a first capacitor, where the control circuit is configured to: turn on the transistor based on a clock signal, integrate the sense current with an integrating capacitor to generate a first voltage, generate a second voltage across the first capacitor based on a first current, generate a second current based on the second voltage, generate a third voltage based on the second current, turn off the transistor when the first voltage becomes higher than the third voltage; discharge the integrating capacitor when the transistor turns off; and regulate an average output current flowing through the inductor based on the first current.

Abstract: The present invention relates to a pressure vessel (1) having a pressure vessel wall (1a) which completely surrounds a reaction chamber (2) as a pressure space for the initiation and/or promotion of chemical and/or physical pressure reactions of a sample (P) to be heated which is accommodated in the reaction chamber (2), wherein the pressure vessel wall (1a) has an infrared-permeable high-pressure window (30) which extends away outward in a direction from the reaction chamber (2) and which is supported in the pressure vessel wall (1a) with respect to a pressure in the reaction chamber (2), wherein the pressure vessel (1) furthermore has an infrared to temperature sensor (40) which is situated directly opposite the high-pressure window (30), in order to measure the temperature of a sample (P), accommodated in the reaction chamber (2), during a pressure reaction through the high-pressure window (30).

Abstract: Provided is a leading-edge protector for a wind turbine rotor blade, including a curved body shaped for attachment to the rotor blade along at least a section of its leading edge; a plurality of fins, each fin extending radially outward from the curved body and terminating in a blunt outer face; and a plurality of reinforcement bands, wherein a reinforcement band is attached to the blunt outer face of a fin. Also provided is a method of manufacturing such a leading-edge protector.

Abstract: Sensors may be located remotely from a rig of a well. The sensors may operate independently of the rig, and generate remote sensor information that characterizes operating characteristics of the well independent of the rig. The operation of the well may be analyzed based on the remote sensor information.