Abstract: An adhesive composition is provided that contains both a hydrophobic phase and a hydrophilic phase, wherein the hydrophobic phase is composed of a crosslinked hydrophobic polymer composition and the hydrophilic phase is a water-absorbent blend of a hydrophilic polymer and a complementary oligomer capable of crosslinking the hydrophilic polymer through hydrogen bonding, ionic bonding, and/or covalent bonding. The composition is useful as a bioadhesive, for affixing drug delivery systems, wound dressings, bandages, cushions, or the like to a body surface such as skin or mucosal tissue.
Type:
Grant
Filed:
May 1, 2002
Date of Patent:
October 12, 2004
Assignees:
Corium International, A.V. Topchiev Institute of Petrochemical Synthsis, Russian
Academy of Sciences
Inventors:
Gary W. Cleary, Mikhail M. Feldstein, Valery G. Kulichikhin, Danir F. Bairamov