Abstract: A milk or other dairy product, capable of minimising the onset of disease such as coronary heart disease or enhancing the immune response is derived from animals which are substantially free of the ?-casein A allele. Bulk milk can be produced by testing for and culling cows who test positive for the ?-casein A allele, or by producing immunoglobulins and other immune response proteins, in cow's milk from animals not possessing the ?-casein A1 allele, or other commercial milk producing animals, to this allele, to counteract the immunosuppressant substances present that are produced from it, in commercial milking cows such as Holsteins, together with its blending with non-treated milk or the recovery of such immunoproteins.

Abstract: A method of reducing the level of saturated fatty acids relative to the level of unsaturated fatty acids in milk. In particular, the genotyping and/or phenotyping of bovine cows on the basis of the amino acid residue located at position 67 of beta-casein produced in their milk. The invention is based on the finding that there is a correlation between the ratio of saturated to unsaturated fatty acids in milk and the beta-casein variants in milk.

Abstract: A milk or other dairy product, capable of minimising the onset of disease such as coronary heart disease or enhancing the immune response is derived from animals which are substantially free of the ?-casein A allele. Bulk milk can be produced by testing for and culling cows who test positive for the ?-casein A allele, or by producing immunoglobulins and other immune response proteins, in cow's milk from animals not possessing the ?-casein A1 allele, or other commercial milk producing animals, to this allele, to counteract the immunosuppressant substances present that are produced from it, in commercial milking cows such as Holsteins, together with its blending with non-treated milk or the recovery of such immunoproteins.

Abstract: This invention relates to a method for determining whether a bovine animal possesses a gene for ?-casein A2 or the gene for ?-casein A1 in its milk by testing the DNA of the bovine animal for the presence of at least one DNA marker (excluding those DNA markers present in the sequence of the genes themselves). In particular, the method uses SNPs as DNA markers for the ?-casein A2 and ?-casein A1 genes.

Abstract: A milk or other dairy product, capable of minimising the onset of disease such as coronary heart disease or enhancing the immune response is derived from animals which are substantially free of the ?-casein A1 allele. Bulk milk can be produced by testing for and culling cows who test positive for the ?-casein A1 allele, or by producing immunoglobulins and other immune response proteins, in cow's milk from animals not possessing the ?-casein A1 allele, or other commercial, milk producing animals, to this allele, to counteract the immunosuppressant substances present that are produced from it, in commercial milking cows such as Holsteins, together with its blending with non-treated milk or the recovery of such immunoproteins.

Abstract: A milk which is free of ?-casein A1 protein in the prevention or treatment of coronary heart disease is disclosed. In addition, a process for the testing of DNA from cells obtained from lactating bovines for the presence of DNA encoding certain ?-casein proteins, selecting the bovines on the basis of the testing, and then milking those bovines to produce milk free of ?-casein A1 for use in the prevention or treatment of coronary heart disease is disclosed.

Abstract: A milk or other dairy product, capable of minimizing the onset of disease such as coronary heart disease or enhancing the immune response is derived from animals which are substantially free of the ?-casein A1 allele. Bulk milk can be produced by testing for and culling cows who test positive for the ?-casein A1 allele, or by producing immunoglobulins and other immune response proteins, in cow's milk from animals not possessing the ?-casein A1 allele, or other commercial milk producing animals, to this allele, to counteract the immnunosuppressant substances present that are produced from it, in commercial milking cows such as Holsteins, together with its blending with non-treated milk or the recovery of such immunoproteins.

Abstract: The invention is based on the discovery that certain variants of &bgr;-casein may induce Type-1 diabetes in susceptible individuals while other variants do not. The invention consists of the selection of non-diabetogenic milk producing cows and recovering and processing their milk and milk products. Another aspect of the invention is selectively breeding cows which produce the non-diabetogenic milk.