Abstract: An implant (prosthesis) comprises biological material in its surface intended to face the body tissue. The surface is formed of a layer (3) consisting of a mixture of grains (5) of tissue-compatible type and disintegrated tissue-compatible biological material (4).In a method of making the implant, an implant body (2) and a mixture of grains (5) of tissue-compatible type and disintegrated tissue-compatible biological material (4) as well as a nutrient solution (6) for the latter are placed in a mould (8). The biological material is allowed to grow in the mould, both out to the boundary wall of the mould cavity and in to the implant body.

Abstract: A method for fixing a joint prosthesis having an outer friction surface includes reaming a cavity in bone structure in which the prosthesis is to be applied and filling the cavity with grains of biologically compatible material. The stem of the prosthesis is driven down into the grain bed until it is substantially surrounded by the grains. The grains are subjected to an external force so that locking and compaction of the grains with respect to each other, and with respect to the prosthesis stem and bone tissue, is brought about. Preferably, the grains are irregular and/or plastic, having a particle size smaller than 5 mm, preferably between 0.5 and 2 mm. The prosthesis stem preferably is driven down into the grain bed by subjecting the grains, via the prosthesis, to vibrations of such a frequency that they are caused to fluidize.

Abstract: The invention comprises a method and a device for fixing a joint prosthesis (1, 2; 5) in which all surfaces intended for tissue contact consist of titanium or a titanium-based tissue-compatible metallic material. For safely anchoring the prosthesis in relation to the bone tissue, use is made of pointed fixing elements (3, 11,16) which from the side of the bone tissue that should be facing the prosthesis are driven into the bone tissue with their pointed portions, and which are anchored in cement (9) between the prosthesis and the bone tissue or directly to the prosthesis, such that a solid connection is established by the bone tissue growing onto the anchored pointed portions. For proper adjustment of the prosthetic joint cup and the prosthetic joint ball, these members are moulded under pressure and heat, each respective articular surface being shaped against a model mould of the mating articular surface, and are hardened or sintered in shape contact for minimizing any aftertreatment.