Abstract: Plant and method for the separation of a gas mixture containing a plurality of gaseous components, comprising first and second membrane-based separation stages and a third gas separation stage with adsorption with oscillating pressure, the first, second and third gas separation stages acting in combination to obtain a first final flow of gas enriched in a first component of the initial gas mixture, for example methane, and a second final flow of gas, enriched in a second component of the initial gas mixture, for example carbon dioxide.