Patents Assigned to Abacus Bioscience, Inc.
  • Therapeutic vaccine for Hepatitis B virus (HBV) using the HBV core antigen
    Patent number: 11883488
    Abstract: Provided herein are compositions of CD1280 binding proteins and a Hepatitis B virus core antigen (HBcAg) and/or a Hepatitis B virus E antigen (HBeAg), or antigenic fragments or mutants thereof, attached to the CD180 binding protein, and methods for using the compositions to treat or limit the development of hepatitis-B virus (HBV)-related disorders.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: January 30, 2024
    Assignee: Abacus Bioscience, Inc.
    Inventors: Edward A. Clark, Deborah L. Fuller, Che-Leung Law, Amanda Mak
  • Therapeutic vaccine for Hepatitis b virus (HBV) using the HBV PreS1 and/or PreS2, and/or s-HBsAg regions of the HBV envelope protein
    Patent number: 11389532
    Abstract: Compositions including a CD180 binding ligand and a linked Hepatitis B antigen and their use are disclosed. The Hepatitis B antigen includes Hepatitis B virus pre-S1 and/or pre-S2 region of the HBV envelope protein (HBVpreS1/S2Ag), L-HBsAg, MHBsAg, S-HBsAg, or antigenic fragments or mutants thereof.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: July 19, 2022
    Assignees: University of Washington, Abacus Bioscience, Inc.
    Inventors: Edward A. Clark, Che-Leung Law, Deborah Fuller, Michael Gale
  • Therapeutic vaccine for Hepatitis b virus (HBV) using the HBV core antigen
    Patent number: 11324819
    Abstract: Provided herein are compositions of CD1280 binding proteins and a Hepatitis B virus core antigen (HBcAg) and/or a Hepatitis B virus E antigen (HBeAg), or antigenic fragments or mutants thereof, attached to the CD180 binding protein, and methods for using the compositions to treat or limit the development of hepatitis-B virus (HBV)-related disorders.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: May 10, 2022
    Assignees: University of Washington, Abacus Bioscience, Inc.
    Inventors: Edward Clark, Deborah L. Fuller, Che-Leung Law, Amanda Mak