Patents Assigned to AbbiVie Inc.
  • Fused heterocyclic derivatives as S1P modulators
    Patent number: 9670220
    Abstract: The present invention relates to a fused heterocyclic derivative of the formula (I) The variables R1-R4, z, A, Q, X and Y are as defined in the claims. The following heterocycles are exemplified sub-structures of formula (I): The compounds of formula (I) are modulators of the S1P receptor (Sphingosine-1-phosphate receptor), More specifically, they are agonists of S1P5. The compounds have therapeutic use in treatment of cognitive disorders, age-relate cognitive decline and dementia.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: June 6, 2017
    Assignees: Abbvie B.V., AbbiVie Inc.
    Inventors: Pieter Smid, Wouter I. Iwema Bakker, Hein K. A. C. Coolen, Leonardus A. J. M. Sliedregt, Maria J. P. van Dongen, Jacobus A. J. den Hartog, Adrian Hobson