Patents Assigned to AbbVie Bahamas Limited
  • (Thio)morpholine derivatives as S1P modulators
    Patent number: 9273017
    Abstract: The present disclosure relates to (thio)morpholine derivatives of the formula (I) or a pharmaceutically acceptable salt, a solvate or hydrate thereof; with the proviso that the derivative of formula (I) is not 2-(4-ethylphenyl)-4-morpholinoethanol or 4-[4-(2-hydroxyethyl)-2-morpholinyl]benzeneacetonitrile or a pharmaceutically acceptable salt, a solvate or hydrate thereof. The compounds of the invention have affinity to S1P receptors and may be used in the treatment, alleviation or prevention of S1P receptor mediated diseases and conditions.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: March 1, 2016
    Assignee: AbbVie Bahamas Limited
    Inventors: Wouter I. Iwema Bakker, Hein K. A. C. Coolen, Axel Stoit, Harmen Mons, Eric Ronken, Elizabeth Van Der Kam, Jurjen Frankena, Adrian Hobson
  • Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HTantagonists
    Patent number: 9126942
    Abstract: This invention concerns arylsulfonyl pyrazoline carboxamidine derivatives as antagonists of 5-ht6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: September 8, 2015
    Assignee: ABBVIE BAHAMAS LIMITED
    Inventors: Arnold van Loevezijn, Wouter I. Iwema Bakker, Alex Stoit, Agatha M. Rensink, Jennifer Venhorst, Martina A.W. Van Der Neut, Martin De Haan, Cornelis G. Kruse
  • (Thio)morpholine derivatives as S1P modulators
    Patent number: 9045441
    Abstract: The present disclosure relates to (thio)morpholine derivatives of the formula (I) or a pharmaceutically acceptable salt, a solvate or hydrate thereof; with the proviso that the derivative of formula (I) is not 2-(4-ethylphenyl)-4-morpholinoethanol or 4-[4-(2-hydroxyethyl)-2-morpholinyl]benzeneacetonitrile or a pharmaceutically acceptable salt, a solvate or hydrate thereof. The compounds of the disclosure have affinity to S1P receptors and may be used in the treatment, alleviation or prevention of S1P receptor mediated diseases and conditions.
    Type: Grant
    Filed: August 27, 2010
    Date of Patent: June 2, 2015
    Assignee: ABBVIE BAHAMAS LIMITED
    Inventors: Wouter I. Iwema Bakker, Hein K. A. C. Coolen, Axel Stoit, Harmen Mons, Eric Ronken, Elizabeth Van Der Kam, Jurjen Frankena, Adrian Hobson
  • Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HTantagonists
    Patent number: 8901108
    Abstract: This invention concerns arylsulfonyl pyrazoline carboxamidine derivatives as antagonists of 5-ht6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis.
    Type: Grant
    Filed: September 11, 2013
    Date of Patent: December 2, 2014
    Assignee: AbbVie Bahamas Limited
    Inventors: Arnold Van Loevezijn, Wouter I. Iwema Bakker, Axel Stoit, Agatha A. M. Rensink, Jennifer Venhorst, Martina A. W. Van Der Neut, Martin De Hann, Cornelis G. Kruse