Abstract: Provided are novel anti-BMPR1B antibodies and antibody drug conjugates, and methods of using such anti-BMPR1B antibodies and antibody drug conjugates to treat cancer.
Type:
Application
Filed:
January 29, 2021
Publication date:
August 26, 2021
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
SOMDUTTA ROY, LAURA SAUNDERS, CASEY FRANKLIN, KEVIN MARTINEZ, SARAH FONG, ZHAO HUANG, SILVIA JUAREZ, ALINA HE, KATHRYN A. LOVING, SANDRO VIVONA
Abstract: Provided are novel anti-SEZ6 antibodies and antibody drug conjugates, and methods of using such anti-SEZ6 antibodies and antibody drug conjugates to treat cancer.
Type:
Grant
Filed:
June 22, 2020
Date of Patent:
August 3, 2021
Assignee:
ABBVIE STEMCENTRX LLC
Inventors:
David Liu, Julia Gavrilyuk, Alexander Schammel
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Type:
Grant
Filed:
December 6, 2019
Date of Patent:
June 15, 2021
Assignee:
AbbVie Stemcentrx LLC
Inventors:
Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
Abstract: Provided are novel anti-BMPR1B antibodies and antibody drug conjugates, and methods of using such anti-BMPR1B antibodies and antibody drug conjugates to treat cancer.
Type:
Grant
Filed:
April 21, 2017
Date of Patent:
March 2, 2021
Assignee:
AbbVie Stemcentrx LLC
Inventors:
Somdutta Roy, Laura Saunders, Casey Franklin, Kevin Martinez, Sarah Fong, Zhao Huang, Silvia Juarez, Alina He, Kathryn A. Loving, Sandro Vivona
Abstract: Anti-PTK7 modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyperproliferative disorders are provided.
Type:
Grant
Filed:
January 29, 2018
Date of Patent:
November 17, 2020
Assignee:
ABBVIE STEMCENTRX LLC
Inventors:
Orit Foord, Scott J. Dylla, Robert A. Stull, Alex Bankovich, Alexandra Leida Liana Lazetic, Jeffrey Bernstein
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Type:
Application
Filed:
December 12, 2019
Publication date:
June 11, 2020
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
LAURA SAUNDERS, SCOTT J. DYLLA, ORIT FOORD, ROBERT A. STULL, MICHAEL TORGOV, HUI SHAO, DAVID LIU
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Type:
Application
Filed:
December 6, 2019
Publication date:
May 7, 2020
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
Robert A. Stull, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao
Abstract: Provided are novel seizure related 6 (SEZ6) modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders.
Type:
Grant
Filed:
June 5, 2017
Date of Patent:
January 14, 2020
Assignee:
ABBVIE STEMCENTRX LLC
Inventors:
Laura Saunders, Scott J. Dylla, Orit Foord, Robert A. Stull, Michael Torgov, Hui Shao, David Liu
Abstract: Provided are novel anti-MFI2 antibodies and antibody drug conjugates, and methods of using such anti-MFI2 antibodies and antibody drug conjugates to treat cancer.
Type:
Grant
Filed:
September 4, 2015
Date of Patent:
October 1, 2019
Assignee:
Abbvie Stemcentrx LLC
Inventors:
Samuel Williams, Laura Saunders, Holger Karsunky, Mandy Boontanrart
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Type:
Application
Filed:
April 12, 2019
Publication date:
August 15, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
ROBERT A. STULL, LAURA SAUNDERS, SCOTT J. DYLLA, ORIT FOORD, DAVID LIU, MICHAEL TORGOV, HUI SHAO
Abstract: Provided are novel anti-DLL3 antibodies and antibody drug conjugates, and methods of using such anti-DLL3 antibodies and antibody drug conjugates to treat brain cancer.
Abstract: Methods of treating tumors at risk for neuroendocrine transition using anti-delta-like ligand 3 (DLL3) antibody drug conjugates (ADCs) are provided.
Type:
Application
Filed:
May 19, 2017
Publication date:
July 4, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
Laura SAUNDERS, Robert A. STULL, Daniel R. HYDUKE, Enying YOU
Abstract: Compositions comprising Achaete-scute homolog 1 (ASCL1) antibodies, and methods comprising ASCL1 antibody compositions for detecting ASCL1 expression as a diagnostic biomarker, are provided.
Type:
Application
Filed:
May 19, 2017
Publication date:
June 27, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
JEFFREY BERNSTEIN, LAURA SAUNDERS, SHEILA BHEDDAH, ENYING YOU, CASEY FRANKLIN, TIEN YIN YAU, GRAYSON KOCHI
Abstract: Provided are novel anti-BMPR1B antibodies and antibody drug conjugates, and methods of using such anti-BMPR1B antibodies and antibody drug conjugates to treat cancer.
Type:
Application
Filed:
April 21, 2017
Publication date:
May 23, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
SOMDUTTA ROY, LAURA SAUNDERS, CASEY FRANKLIN, KEVIN MARTINEZ, SARAH FONG, ZHAO HUANG, SILVIA JUAREZ, ALINA HE, KATHRYN A. LOVING, SANDRO VIVONA
Abstract: Provided are novel anti-TNFRSF21 antibodies and antibody drug conjugates, and methods of using such anti-TNFRSF21 antibodies and antibody drug conjugates to treat cancer.
Type:
Application
Filed:
May 5, 2017
Publication date:
May 2, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
LAURA SAUNDERS, DEEPTI ROKKAM, DAVID LIU, MANDY BOONTANRART, ALEXANDER JOHN BANKOVICH, EVAN BISHOP, MONETTE AUJAY, ZHAO HUANG
Abstract: Provided herein are novel anti-CLDN antibodies and antibody drug conjugates (ADC), including derivatives thereof, and methods of using the same to treat proliferative disorders.
Type:
Application
Filed:
December 2, 2016
Publication date:
March 21, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
SARAH FONG, VIKRAM NATWARSINHJI SISODIYA, ROBERT A. STULL, SAMUEL A. WILLIAMS
Abstract: Provided herein are novel anti-CLDN antibodies and antibody drug conjugates (ADC), including derivatives thereof, and methods of using the same to treat proliferative disorders.
Type:
Application
Filed:
August 20, 2018
Publication date:
March 14, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
Marianne SANTAGUIDA, Monette AUJAY, Laura SAUNDERS, David LIU, Orit FOORD, Robert A. STULL, Paul Anthony ESCARPE
Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
Type:
Application
Filed:
October 25, 2018
Publication date:
February 14, 2019
Applicant:
ABBVIE STEMCENTRX LLC
Inventors:
ROBERT A. STULL, Laura Saunders, Scott J. Dylla, Orit Foord, David Liu, Michael Torgov, Hui Shao