Patents Assigned to ABCAM PLC
  • Site-directed CRISPR/recombinase compositions and methods of integrating transgenes
    Patent number: 10975392
    Abstract: Disclosed herein are targeted chimeric polypeptides, compositions thereof, expression vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors, and methods of the present invention are also useful in gene therapy and cell therapy techniques. The chimeric polypeptide includes a CRISPR-Cas domain and a recombinase domain.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: April 13, 2021
    Assignee: ABCAM PLC
    Inventor: Ruby Yanru Tsai