Patents Assigned to Abcentra, LLC
  • Methods for treatment of rheumatoid arthritis and accelerated atherosclerosis with an anti-Apo B100 antibody
    Patent number: 11690912
    Abstract: Compositions and methods for treating rheumatoid arthritis and/or accelerated atherosclerosis are provided, including an inhibitor of oxidized or malondialdehyde-modified low density lipoprotein (LDL) for administration to a subject. Exemplary inhibitors of oxidized LDL include an anti-oxidized LDL antibody, which results in a reduction in the secretion of pro-inflammatory cytokine from primary monocyte in vitro and the plasma cytokine level of inflammatory cytokine in vivo.
    Type: Grant
    Filed: May 29, 2019
    Date of Patent: July 4, 2023
    Assignee: Abcentra, LLC
    Inventors: Bertrand C. Liang, Stacey Ruiz, Christopher John Farina
  • Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
    Patent number: 10858422
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: December 8, 2020
    Assignee: Abcentra, LLC
    Inventors: Jan Nilsson, Ryan Benjamin Abbott, Bertrand C. Liang, Christopher John Farina, Stacey Ruiz
  • Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
    Patent number: 10434141
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: October 8, 2019
    Assignee: Abcentra, LLC
    Inventors: Jan Nilsson, Ryan Benjamin Abbott
  • METHODS FOR DIAGNOSING AND TREATING SYSTEMIC LUPUS ERYTHEMATOSUS WITH AN ANTI-APOLIPOPROTEIN B ANTIBODY
    Publication number: 20190284268
    Abstract: Described herein are peptides and antibodies for prevention and/or therapeutic treatment of mammals, including humans, against systemic lupus erythematosus, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing SLE and/or to disease grading, staging, and/or prognosis.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 19, 2019
    Applicant: Abcentra, LLC
    Inventors: Jan Nilsson, Ryan Benjamin Abbott, Bertrand C. Liang, Christopher John Farina, Stacey Ruiz