Abstract: A delivery device for intravenous delivery of microparticles to a patient. The delivery device is fluidly connectable to (i) a first source of an injection medium and (ii) a second source of an injection medium. The delivery device includes: a first fluid inlet fluidly connectable to the first source of the injection medium, a fluid outlet, a fluid mixer fluidly connecting the first fluid inlet to the fluid outlet, a second fluid inlet fluidly connectable to the second source of the injection medium, and a source of microparticles fluidly connecting the second fluid inlet to the fluid mixer. When fluid flows from the second source of the injection medium into the delivery device: the second injection medium fluidly drives microparticles from the source of microparticles into the fluid mixer, and the fluid outlet dispenses to the patient an injection medium that includes the microparticles.
Type:
Grant
Filed:
October 18, 2019
Date of Patent:
November 22, 2022
Assignee:
ABK Biomedical Incorporated
Inventors:
David Mark Douglas Hodgson, Marc Andre Gregoire, Kathryn Margaret Ann Atwell, Gary Michael Donofrio, Robert Joseph Abraham, Evan Christopher Wiens, Brenna Catherine Kettlewell
Abstract: Provided are radiopaque compositions comprising one or more of yttrium (Y), strontium (Sr), gallium (Ga), and silicon, or oxides and salts thereof. The composition can comprise a combination of Y2O3, SrO, Ga2O3, and SiO2, and optionally MnO2, and TiO2. Other compositions comprise SrO, Ga2O3, TiO2, MnO2, and SiO2. The composition can be a particulate material. The compositions are useful for radioembolization to treat tumors.
Type:
Grant
Filed:
November 26, 2015
Date of Patent:
August 10, 2021
Assignee:
ABK Biomedical Incorporated
Inventors:
Daniel Boyd, Robert Joseph Abraham, Xiaofang Zhang, Sharon Legere, James Clarke
Abstract: A radiopaque particulate material one or more of SiO2, TiO2, La2O3, Na2O and MgO and useful for embolization which optionally includes therapeutic components that are released in vivo.
Type:
Grant
Filed:
January 27, 2012
Date of Patent:
September 12, 2017
Assignee:
ABK Biomedical Incorporated
Inventors:
Robert J. Abraham, Sharon Kehoe, Daniel Boyd