Abstract: Presented herein are compositions and methods for preventing, reducing, delaying and treating a coronavirus infection and related disorders such as respiratory distress, disseminated intravascular coagulation, and central nervous system pathologies caused by coronavirus infection.
Type:
Grant
Filed:
January 11, 2022
Date of Patent:
March 26, 2024
Assignee:
ABREXA PHARMACEUTICALS, INC.
Inventors:
Jesus E. Villafranca, Charles Richard Kissinger
Abstract: Crystalline polymorph forms of neurotrophic agent 2,2,2-trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide (J147), and process for producing the crystalline polymorphic form are provided.
Type:
Grant
Filed:
January 17, 2021
Date of Patent:
February 21, 2023
Assignee:
ABREXA PHARMACEUTICALS, INC.
Inventors:
Michael O'Neill, Barbara Kidon, William A. Janz, Hongqiao Wu
Abstract: Crystalline polymorph forms of neurotrophic agent 2,2,2-trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide (J147), and process for producing the crystalline polymorphic form are provided.
Type:
Grant
Filed:
February 20, 2019
Date of Patent:
April 6, 2021
Assignee:
ABREXA PHARMACEUTICALS, INC.
Inventors:
Michael O'Neill, Barbara Kidon, William A. Janz, Hongqiao Wu