Abstract: The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal superantigen (SAg) proteins, or any fragments, variants, or derivatives thereof fused together as a single polypeptide in any order.
Type:
Grant
Filed:
February 25, 2022
Date of Patent:
November 28, 2023
Assignee:
ABVACC, Inc.
Inventors:
Mohammad Javad Aman, Thomas Kort, Arundhathi Venkatasubramaniam, Nils Williston, Rajan Prasad Adhikari, Frederick W. Holtsberg