Patents Assigned to ACADEMIC HOSPITAL MAASTRICHT
  • Method for improving cartilage repair and/or preventing cartilage degeneration in a joint
    Patent number: 8962666
    Abstract: The invention is in the field of methods for medical treatment. It provides an improved method for repairing damaged cartilage and/or preventing cartilage degeneration in tissue, in particular in a joint by administering a pharmaceutically active agent directly into the fat pad of a joint. The pharmaceutically active agent is preferably selected from the group consisting of agents that stimulate chondrogenic differentiation and/or cartilage matrix synthesis; agents that inhibit osteogenesis and/or hypertrophy, anti-inflammatory agents, agents that inhibit apoptosis of chondrocytes, agents that inhibit senescence of chondrocytes and agents that enhance lubrication of a joint.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: February 24, 2015
    Assignees: Maastricht University, Academic Hospital Maastricht
    Inventors: Peter Joseph Emans, Lodewijk Willem Van Rhijn, Tim Johannes Maria Welting, Mike De Leeuw
  • METHOD FOR IMPROVING CARTILAGE REPAIR AND/OR PREVENTING CARTILAGE DEGENERATION IN A JOINT
    Publication number: 20130123314
    Abstract: The invention is in the field of methods for medical treatment. It provides an improved method for repairing damaged cartilage and/or preventing cartilage degeneration in tissue, in particular in a joint by administering a pharmaceutically active agent directly into the fat pad of a joint. The pharmaceutically active agent is preferably selected from the group consisting of agents that stimulate chondrogenic differentiation and/or cartilage matrix synthesis; agents that inhibit osteogenesis and/or hypertrophy, anti-inflammatory agents, agents that inhibit apoptosis of chondrocytes, agents that inhibit senescence of chondrocytes and agents that enhance lubrication of a joint.
    Type: Application
    Filed: November 14, 2012
    Publication date: May 16, 2013
    Applicants: ACADEMIC HOSPITAL MAASTRICHT, MAASTRICHT UNIVERSITY
    Inventors: Maastricht University, Academic Hospital Maastricht
  • METHOD FOR IMPROVING CARTILAGE REPAIR AND/OR PREVENTING CARTILAGE DEGENERATION IN A JOINT
    Publication number: 20100215731
    Abstract: The invention is in the field of methods for medical treatment. It provides an improved method for repairing damaged cartilage and/or preventing cartilage degeneration in tissue, in particular in a joint by administering a pharmaceutically active agent directly into the fat pad of a joint. The pharmaceutically active agent is preferably selected from the group consisting of agents that stimulate chondrogenic differentiation and/or cartilage matrix synthesis; agents that inhibit osteogenesis and/or hypertrophy, anti-inflammatory agents, agents that inhibit apoptosis of chondrocytes, agents that inhibit senescence of chondrocytes and agents that enhance lubrication of a joint.
    Type: Application
    Filed: February 19, 2010
    Publication date: August 26, 2010
    Applicants: MAASTRICHT UNIVERSITY, ACADEMIC HOSPITAL MAASTRICHT
    Inventors: Peter Joseph Emans, Lodewijk Willem Van Rhijn, Tim Johannes Maria Welting, Mike De Leeuw