Abstract: The invention relates to the use of an agonist of one or more of the nuclear receptors TR3, MINOR and NOT for the preparation of a medicament for the treatment of cardiovascular disease, in particular in-stent restenosis and/or vein-graft disease. The invention further relates to medical devices, such as stents and cuffs, that are coated with the agonist, or in which the agonist is incorporated and which are for use in the treatment of in-stent restenosis or vein-graft disease.
Type:
Application
Filed:
June 15, 2006
Publication date:
February 5, 2009
Applicant:
ACADEMISCH MEDISCH CENTRUM, BUREAU
Inventors:
Caroline Jacoba Maria De Vries, Hans Pannekoek, Vivian De Waard, Elisabeth Karin Arkenbout