Patents Assigned to Acambis Inc.
  • Chimeric flavivirus vectors
    Patent number: 7569383
    Abstract: The invention provides chimeric flavivirus vectors including foreign peptides inserted into the envelope proteins of the vectors and methods of using these vectors.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: August 4, 2009
    Assignee: Acambis Inc.
    Inventors: Harold Kleanthous, Charles Miller, Larisa Oros
  • West nile virus vaccine
    Patent number: 7507415
    Abstract: The invention provides chimeric flavivirus vaccines against West Nile virus and methods of using these vaccines to prevent or treat West Nile virus infection.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: March 24, 2009
    Assignee: Acambis Inc.
    Inventors: Juan Arroyo, Charles Miller, John Avram Catalan, Thomas P. Monath
  • Chimeric flaviviruses
    Patent number: 7459160
    Abstract: The invention provides flavivirus vaccines and methods of making and using these vaccines.
    Type: Grant
    Filed: January 15, 2003
    Date of Patent: December 2, 2008
    Assignee: Acambis Inc.
    Inventors: Thomas P. Monath, Farshad Guirakhoo, Juan Arroyo, Konstantin Pugachev
  • Vaccination Against Dengue Virus Infection
    Publication number: 20080193477
    Abstract: This invention relates to methods and kits for use in vaccination against dengue virus infection.
    Type: Application
    Filed: August 9, 2006
    Publication date: August 14, 2008
    Applicants: Acambis Inc., Sanofi Pasteur SA
    Inventors: Thomas P. Monath, Farshad Guirakhoo, Niranjan Kanesa-thasan, Thomas H. Ermak, Jean Lang, Remi Forrat
  • Recombinant Flavivirus Vaccines
    Publication number: 20080175862
    Abstract: The invention provides recombinant flavivirus vaccines that can be used in the prevention and treatment of flavivirus infection. The vaccines of the invention contain recombinant flaviviruses including attenuating mutations.
    Type: Application
    Filed: April 24, 2006
    Publication date: July 24, 2008
    Applicant: Acambis Inc.
    Inventors: Konstantin V. Pugachev, Farshad Guirakhoo, Thomas P. Monath
  • Vaccines Against Japanese Encephalitis Virus and West Nile Virus
    Publication number: 20070269458
    Abstract: The invention provides attenuated Flavivirus vaccines, such as vaccines against Japanese encephalitis virus and West Nile virus, as well as methods of making and using these vaccines.
    Type: Application
    Filed: October 19, 2005
    Publication date: November 22, 2007
    Applicant: Acambis Inc.
    Inventors: Farshad Guirakhoo, Jian Liu, John Catalan, Thomas Monath, Konstantin Pugachev
  • Immunization Against Clostridium Difficile Disease
    Publication number: 20070231336
    Abstract: The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
    Type: Application
    Filed: May 30, 2007
    Publication date: October 4, 2007
    Applicant: Acambis Inc.
    Inventors: William Thomas, Paul Giannasca, Zhenxi Zhang, Wende Lei, Thomas Monath
  • Smallpox vaccine
    Patent number: 7115270
    Abstract: The invention provides attenuated vaccinia virus vaccines that can be used in methods to prevent or treat small pox in patients, as well as methods of obtaining such vaccines.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: October 3, 2006
    Assignee: Acambis Inc.
    Inventors: Richard A. Weltzin, Thomas P. Monath
  • Active immunization against clostridium difficile disease
    Patent number: 6969520
    Abstract: The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: November 29, 2005
    Assignee: Acambis Inc.
    Inventors: William D. Thomas, Jr., Paul J. Giannasca, Zhenxi Zhang, Wende Lei, Thomas P. Monath
  • Methods of preventing and treating flavivirus infection in animals
    Patent number: 6878372
    Abstract: The invention provides methods of preventing and treating flavivirus infection in animals.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: April 12, 2005
    Assignee: Acambis Inc.
    Inventors: Thomas P. Monath, Juan Arroyo