Abstract: A ceiling tile clip includes a top wall, a pair of parallel, spaced side walls that extend downwardly from opposite edges of the top wall and flanges at lower edges of the side walls that extend outwardly. The top wall includes a threaded opening in the center thereof. The ceiling tile clip is configured to be attached to an elongated ceiling grid member by a threaded member that threadedly engages the threaded opening. The elongated ceiling grid member has side surfaces and lower flange portions. When the ceiling tile clip is attached to the elongated ceiling grid member, the top wall of the ceiling tile clip is above the elongated ceiling grid member, the side walls of the ceiling tile clip are alongside the side surfaces of the elongated ceiling grid member and the flanges of the ceiling tile clip are above the flange portions.

Abstract: Various methods employing transvascular access devices are described, including a method of placing a central catheter in a peripheral vein in an arm of a patient; a method of providing percutaneous access to the heart of a patient; a method of clearing a clotted arteriovenous dialysis graft; a method of creating multiple access points into a single blood vessel; a method of creating an AV fistula in a patient; and a method of providing a bypass to a blockage in a popliteal artery in a patient.

Abstract: Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier.

Abstract: A system for foreign material accountability includes a kiosk, which further includes a touch enabled display screen that is back-lit and automatically adjusts brightness based on ambient environment. A user input device, wherein the user input device includes a pin pad, one or more sensors selected from a group consisting of temperature sensors, RFID sensors, IR sensors, optical sensors, iris sensors and one or more cameras, a processor, a data bus coupled to the processor and a computer-usable medium embodying computer code operating on the kiosk. The computer code includes programmed instructions executable by the processor to control accessibility of items into a restricted area based on data received from at least one of the display screen operated by a user, the user input device, and the one or more sensors.

Abstract: The present disclosure relates to methods and compositions for treating a active tuberculosis infection and methods and compositions for improving the efficacy of chemotherapy regimens against active tuberculosis infection. The present disclosure relates to methods of treating an active M. tuberculosis infection or an active infection resulting from reactivation of a latent infection in a mammal and to methods of improving the efficacy of chemotherapy regimens against active M. tuberculosis infection.

Abstract: A magnetizing system for use in selectively magnetizing a needle of a medical device is disclosed. Once magnetized, the needle can be tracked by a needle guidance system, which assists the clinician placing the needle by visualizing on a display the position and orientation of the needle after its insertion into a body of a patient. An orientation key system is included with the magnetizing system to ensure the needle is positioned correctly in the magnetizing system. This in turn ensures that the needle is properly magnetized so as to be accurately tracked by the needle guidance system. In one embodiment a first key is included with the magnetizing system and configured to cooperatively mate with a second key included with the needle of the medical device. Various types of keys are disclosed herein.

Abstract: A ceiling tile clip includes a top wall, a pair of parallel, spaced side walls that extend downwardly from opposite edges of the top wall and flanges at lower edges of the side walls that extend outwardly. The top wall includes a threaded opening in the center thereof. The ceiling tile clip is configured to be attached to an elongated ceiling grid member by a threaded member that threadedly engages the threaded opening. The elongated ceiling grid member has side surfaces and lower flange portions. When the ceiling tile clip is attached to the elongated ceiling grid member, the top wall of the ceiling tile clip is above the elongated ceiling grid member, the side walls of the ceiling tile clip are alongside the side surfaces of the elongated ceiling grid member and the flanges of the ceiling tile clip are above the flange portions.

Abstract: A UV reactor for disinfecting water. The UV reactor may include a cooling chamber in which heat from a UV source may be transferred to the water flowing through the UV reactor. The UV reactor may include driver circuitry operable to determine status information, such as health, of the UV source. The UV reactor may include a gas discharge path operable to substantially prevent accumulation of gas within a water treatment chamber.

Abstract: A portable and passive safety intraosseous device to allow for direct introduction of medications, etc., within the intermedullary space of a subject patient's bone or, if needed, the removal of certain substances from such a subject patient's bone. Such a device permits direct drilling and placement of a cannula within the subject bone with access external to the subject patient's skin, permitting, as well, connection of a tube for such introduction/removal purposes. The ability to provide a passive safety unit allows for facilitated utilization in, for instance, emergency situations with the entire device provided for utilization thereof. The device includes a drilling component with a permanently attached stylet and a removable cannula, a power supply for a single drilling operation, a mechanism to draw the stylet back into the drill component after use and disengagement from the cannula, and an automatic closure that activates with the separation of the cannula.

Abstract: Stable aqueous formulations of adjuvant comprising a TLR7/8 agonist or a TLR4 agonist with a helper lipid that are adsorbed to alum are provided. Compositions and methods of using the formulations for stimulating an immune response are also provided.

Abstract: An ergonomically designed smart wristband for clinical-grade multiparameter monitoring is disclosed. The smart wristband incorporates multiple sensors including custom-designed reflective arterial pulse sensors, a thermopile sensor, and electrocardiogram (ECG) electrodes. When the smart wristband is worn on the wrist, the biosensors contact the skin. The smart wristband may tether wirelessly to a mobile or any other computing device to continuously acquire and stream information like arterial pulse waveform and temperature data. Algorithms running on the computing device or onboard microprocessor analyze the acquired data to report parameters like blood pressure, body temperature, respiration, and blood oxygen. The device can also operate in a fully-standalone mode to accomplish continuous multiparameter physiological monitoring, analysis, and reporting.

Abstract: Disclosed are a package structure of an integrated passive device and a manufacturing method thereof and a substrate. The method includes: providing an organic frame having a chip embedding cavity and a metal pillar, laminating at least one layer of first dielectric on an upper surface of the organic frame, and processing the first dielectric by photolithography to form an opening correspondingly above the chip embedding cavity; mounting an electronic component in the chip embedding cavity through the opening, the electronic component including an upper and lower electrodes; laminating and curing a second dielectric into the chip embedding cavity and on an upper surface of the first dielectric, thinning the first and second dielectrics to expose the upper and lower electrodes, upper and lower surfaces of the metal pillar; performing metal electroplating to form a circuit layer communicated with the upper and lower electrodes and the metal pillar.

Abstract: In one aspect the present invention provides a door strike which prevents the opening of an associated door when the door strike has been heated to an elevated temperature of at least about 1000° F., preferably when the door strike is at higher temperatures such as are present during a fire in a building structure. The door strike includes a thermally responsive element which retards the normal operation of the door strike when it is at an elevated temperature. A further aspect of the invention is a method for controlling the undesired spread of a fire or smoke between adjacent spaces separated by the door wherein a fire or smoke condition exists in at least one of these spaces, via the provision of a door strike having a thermally responsive element which retards the normal operation of the door strike when it is at an elevated temperature.

Abstract: Zippered curved screen flap access panels, systems, arrangements, kits and methods for making a zippered curved screen flap panels in order to access space on another side of a screen enclosure. In a preferred embodiment, the novel curved screen flap can be formed in a screen panel, where the panel is installed in an upper location of a screen cage such as in a roof section or upper wall section below or adjacent to a roof gutter. The panel can be easily unzipped with the flap hanging down so that the gutter can be easily accessed and cleaned through the access opening. After the gutter is cleaned, the flap can easily be zippered back in place with the screen material being retensioned.

Abstract: A tool for adjusting the backset of a latch bolt. The latch bolt includes a latch bolt and a tailpiece. A housing receives the latch bolt and includes a transversely extending protrusion. A casing slidably receives the housing such that the protrusion on the housing is received in a slot on the casing and an inner end of the tailpiece extends from the housing and casing. The casing is rotated relative to the housing to allow relative axial movement between the casing and the housing when transitioning between the first backset position and the second backset position. The tool includes a member defining a first slot for receiving the inner end of the tailpiece and a pair of second slots for receiving the pair of ears such that rotation of the tool rotates the tailpiece and the casing simultaneously.

Abstract: Valve assemblies having improved ability to selectively control flow of fluids through the catheter and prevent leakage of fluids from the proximal end of a catheter that is positioned within a patient. Such improved catheter valve assemblies also prevent leakage of fluids after repeated insertion and removal of medical instruments through the valve.

Abstract: A door exit device may include a light source for indicating a status of the exit device. The light source may be capable of providing a first indication denoting that the exit device is in a first state (e.g., a dogged state) and a second indication denoting that the exit device is in a second state (e.g., an undogged state). Further, the exit device may include first and second parallel control systems capable of electronically controlling that status of the exit device. In some instances, a first parallel control system may supersede a second parallel control system.

Abstract: Methods and devices to facilitate positioning of a catheter into a vessel. Devices include axially concentric assemblies of a piercing cannula, a shield and tubing such as a catheter where the shield can be passively or actively locked into position over the cannula tip to prevent inadvertent needle sticks.

Abstract: A hermetic seal between an optical element and a metal mount or housing using a fluoropolymer. The fluoropolymer is dispersed along the interior edge of the metal mount. The metal mount and fluoropolymer are then heated to a temperature exceeding the melting point of the fluoropolymer. Once heated the optical element is pressed into the metal mount and allowed to cool. The metal mount, optical element and thickness of fluoropolymer are sized to provide an interference fit between the metal mount and optical element.

Abstract: Provided is a connection member that is to be bridged between a seat back and a luggage room floor, and stretches and contracts as at least one of the seat back and the luggage room floor moves. The connection member has a main body portion formed into the shape of a thin plate or a sheet; and a plurality of long convex portions provided on the main body portion in a parallel manner. The long convex portions are extendedly provided in a direction orthogonal to a direction along which the connection member stretches and contracts. As the seat back and the luggage room floor approach each other, a first bending portion and second bending portion having the plurality of the long convex portions will be bended in a manner such that the plurality of the long convex portions will be positioned inward.