Abstract: A portable hand-held miniature vein enhancer comprises: a housing, laser, one or more mirrors, mirror drive system, and sensor to determine a distance to the target. The laser emits a beam of light at a selective wavelength that images subcutaneous veins through differential absorption and reflection. The mirror(s) receive the beam of light and create a spot of light on the target, and when driven by the mirror drive system to oscillate, the spot is scanned to form a two-dimensionally shaped pattern of light. The scanned spot of light moves according to a range of angular positions of the mirror(s). When the distance to the target is at or below a threshold distance, the range of angular positions is set to a maximum, producing the largest scan pattern. When the distance increases beyond the threshold, the range of angular positions is reduced proportional to the increased distance.

Abstract: A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of florescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the florescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.