Patents Assigned to ACERUS BIOPHARMA INC.
  • Medicament delivery device and method
    Patent number: 11793950
    Abstract: A medicament delivery device is provided having an oral tubular section for placement in the mouth of a user and a nasal tubular section for placement in the naris of a user. A medicament located in a corrugated, or flexible, section joining the oral tubular section and the nasal tubular section is dispersed into the nasal cavity of the user by blowing into the oral tubular section. A pinch valve or a one way valve is used to prevent the user from accidentally inhaling the medicament. The medicament delivery device may also be used as a pulmonary delivery device into the mouth of a user.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: October 24, 2023
    Assignees: PROPEL-AIR BIOPHARMA, LLC, ACERUS BIOPHARMA INC.
    Inventor: Ari Isaacs
  • Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
    Patent number: 11744838
    Abstract: The present invention relates to methods of treating hypogonadism in a male subject through administering intranasally to the male subject an intranasal testosterone bio-adhesive gel formulation to deliver a therapeutically effective amount of testosterone. In particular, the testosterone therapy of the invention remains effective if an allergic rhinitis event occurs in the male during the treatment or when the male subject uses a topical nasal vasoconstrictor or a topical intranasal decongestant during the hypogonadism treatment. Further, the present invention relates to a method of preventing the occurrence of an allergic rhinitis event in a male, who is undergoing a hypogonadism treatment with an intranasal testosterone bio-adhesive gel. In certain embodiments, the intranasal testosterone bio-adhesive gel formulation according to the invention comprises 4.0% and 4.5% testosterone.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: September 5, 2023
    Assignee: ACERUS BIOPHARMA INC.
    Inventor: Natalia Tkachenko
  • Methods of treating hypogonadism with transnasal testerosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event
    Patent number: 11090312
    Abstract: The present invention relates to methods of treating hypogonadism in a male subject through administering intranasally to the male subject an intranasal testosterone bio-adhesive gel formulation to deliver a therapeutically effective amount of testosterone. In particular, the testosterone therapy of the invention remains effective if an allergic rhinitis event occurs in the male during the treatment or when the male subject uses a topical nasal vasoconstrictor or a topical intranasal decongestant during the hypogonadism treatment. Further, the present invention relates to a method of preventing the occurrence of an allergic rhinitis event in a male, who is undergoing a hypogonadism treatment with an intranasal testosterone bio-adhesive gel. In certain embodiments, the intranasal testosterone bio-adhesive gel formulation according to the invention comprises 4.0% and 4.5% testosterone.
    Type: Grant
    Filed: June 18, 2020
    Date of Patent: August 17, 2021
    Assignee: Acerus Biopharma Inc.
    Inventor: Natalia Tkachenko
  • Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
    Patent number: 10668084
    Abstract: The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the lower dosage strength pernasal testosterone gel formulations for treating a female subject with anorgasmia and/or hypoactive sexual desire disorder.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: June 2, 2020
    Assignee: Acerus Biopharma Inc.
    Inventors: Wayne Kreppner, Siobhan Fogarty, Werner Oberegger, Paul José Pierre Marie Maes
  • Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder
    Patent number: 10111888
    Abstract: The present invention relates to lower dosage strength pernasal testosterone gel formulations for intranasal administration and treatment methods for using the lower dosage strength pernasal testosterone gel formulations for treating a female subject with anorgasmia and/or hypoactive sexual desire disorder.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: October 30, 2018
    Assignee: ACERUS BIOPHARMA INC.
    Inventors: Wayne Kreppner, Siobhan Fogarty, Werner Oberegger, Paul José Pierre Marie Maes