Abstract: The present invention provides a family of novel cytotoxic pentapeptides, which show potent antitumor activities against several cancer lines. The antibody-drug conjugates prepared from those pentapeptides can efficiently kill cancer cells.
Type:
Application
Filed:
February 15, 2016
Publication date:
June 9, 2016
Applicant:
ACES Pharma Inc.
Inventors:
Shanghui Hu, Lucy Xiumin Zhao, Jinying Ning, Xufang Tian, Chao Li, Wei Hu, Xu Liu, Bonnie Y. Hu
Abstract: The present invention provides a family of novel cytotoxic pentapeptides, which show potent antitumor activities against several cancer lines. The antibody-drug conjugates prepared from those pentapeptides can efficiently kill cancer cells.