Patents Assigned to ACGT ProGenomics AG
  • Patent number: 7981676
    Abstract: The invention relates to a method for the transfer of molecular substances, for example proteins or nucleic acids in cells, in the case of using DNA combined with a possible gene expression. A prokaryotic nucleic acid-binding protein is used for the transfer, which is preferably obtained from a thermostable organism. Where the substance to be transferred is a nucleic acid, the protein forms a reversible complex with the nucleic acid. The prokaryotic protein condenses and compacts the nucleic acids. Said nucleic acids can be taken up in the target cells after suitable incubation.
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: July 19, 2011
    Assignee: ACGT Progenomics AG
    Inventors: Gerald Boehm, Dirk Esser
  • Publication number: 20090155912
    Abstract: The invention relates to a method for the transfer of molecular substances, for example proteins or nucleic acids in cells, in the case of using DNA combined with a possible gene expression. A prokaryotic nucleic acid-binding protein is used for the transfer, which is preferably obtained from a thermostable organism. Where the substance to be transferred is a nucleic acid, the protein forms a reversible complex with the nucleic acid. The prokaryotic protein condenses and compacts the nucleic acids. Said nucleic acids can be taken up in the target cells after suitable incubation.
    Type: Application
    Filed: September 9, 2008
    Publication date: June 18, 2009
    Applicant: ACGT ProGenomics AG
    Inventors: Gerald Boehm, Dirk Esser
  • Patent number: 7488605
    Abstract: The present invention relates to a method for characterising and optionally separating molecular associates, especially particles having a size smaller than 300 nm. Partial units of the molecular associates are used as markers, whereby said units are marked with fluorescent dyes. The marked associates and aggregates are characterised by means of a FACS (fluorescence-activated cell sorter).
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: February 10, 2009
    Assignee: ACGT ProGenomics AG
    Inventors: Gerald Boehm, Ulrich Schmidt
  • Patent number: 7435595
    Abstract: The invention relates to a method for the transfer of molecular substances, for example proteins or nucleic acids in cells, in the case of using DNA combined with a possible gene expression. A prokaryotic nucleic acid-binding protein is used for the transfer, which is preferably obtained from a thermostable organism. Where the substance to be transferred is a nucleic acid, the protein forms a reversible complex with the nucleic acid. The prokaryotic protein condenses and compacts the nucleic acids. Said nucleic acids can be taken up in the target cells after suitable incubation.
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: October 14, 2008
    Assignee: ACGT ProGenomics AG
    Inventors: Gerald Boehm, Dirk Esser
  • Patent number: 7091028
    Abstract: The invention relates to a method for packaging molecular substances in protein shells, comprising the following steps: binding a protein shell fragment, via a first region to a matrix; bringing the protein shell fragment bound to the matrix into contact with the molecular substance, in order to bind the molecular substance to a second region of the protein shell fragment; separating the protein shell fragment with the bonded molecular substance, or the part thereof which contains the bonded molecular substance, from the matrix and assembling the separated protein shell fragments, or the part thereof which contains the bonded molecular substance, with other protein shell fragments to form a protein shell, whereby the separation and assembly can be carried out in any order.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: August 15, 2006
    Assignee: ACGT ProGenomics AG
    Inventors: Gerald Boehm, Dirk Esser, Ulrich Schmidt
  • Publication number: 20050266020
    Abstract: The invention relates to transport systems for molecular substances, comprising a mosaic of recombinant partial units (individual components). The invention further relates to production of the molecular transport system and use thereof.
    Type: Application
    Filed: May 2, 2005
    Publication date: December 1, 2005
    Applicant: ACGT ProGenomics AG
    Inventors: Gerald Boehm, Rainer Rudolph, Ulrich Schmidt, Dirk Esser
  • Publication number: 20050170504
    Abstract: The invention relates to a method for the transfer of molecular substances, for example proteins or nucleic acids in cells, in the case of using DNA combined with a possible gene expression. A prokaryotic nucleic acid-binding protein is used for the transfer, which is preferably obtained from a thermostable organism. Where the substance to be transferred is a nucleic acid, the protein forms a reversible complex with the nucleic acid. The prokaryotic protein condenses and compacts the nucleic acids. Said nucleic acids can be taken up in the target cells after suitable incubation.
    Type: Application
    Filed: September 29, 2004
    Publication date: August 4, 2005
    Applicant: ACGT ProGenomics AG
    Inventors: Gerald Boehm, Dirk Esser
  • Publication number: 20050069935
    Abstract: The present invention relates to a method for characterising and optionally separating molecular associates, especially particles having a size smaller than 300 nm. Partial units of the molecular associates are used as markers, whereby said units are marked with fluorescent dyes. The marked associates and aggregates are characterised by means of a FACS (fluorescence-activated cell sorter).
    Type: Application
    Filed: September 23, 2004
    Publication date: March 31, 2005
    Applicant: ACGT ProGenomics AG
    Inventors: Gerald Boehm, Ulrich Schmidt