Patents Assigned to Acrux DDS PTY LTD
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Patent number: 8435944Abstract: The invention is directed to a transdermal drug delivery composition which includes at least one physiologically active agent; and at least one volatile solvent; and at least one viscosity modulating agent. The invention extends to methods of administering such a composition to a subject and treatment of subjects using the composition.Type: GrantFiled: June 2, 2006Date of Patent: May 7, 2013Assignee: Acrux DDS Pty Ltd.Inventors: Tony Dipietro, Andrew Humberstone, Igor Gonda, Adam Watkinson, Kerrie Setiawan, Nina Wilkins
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Patent number: 8419307Abstract: Described are methods comprising applying a liquid pharmaceutical testosterone composition with an implement comprising a support and a receptacle mounted on the support and defining a reservoir space with an open top to receive the liquid, wherein the receptacle includes a flexible membrane integrally forming a base and a wall, the wall being substantially transverse to the base and having a working surface to spread the liquid over the treatment surface, wherein the base has a continuous surface such that liquid cannot pass through the base, wherein the wall includes an inner portion which extends from the base to an upper end and an outer skirt portion, wherein the inner portion and skirt portion form a double-wall structure, and wherein at least the wall is resiliently deformable so the working surface maintains contact with the treatment surface when spreading the liquid.Type: GrantFiled: May 4, 2012Date of Patent: April 16, 2013Assignee: Acrux DDS Pty Ltd.Inventors: Peter Bayly, Mark Simon Bayly, Magnus Ahlstrom, Adam Charles Watkinson
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Patent number: 8357393Abstract: A pharmaceutical composition for transdermal delivery comprising one or more physiologically active agents; one or more dermal penetration enhancers; and a volatile pharmaceutically acceptable carrier comprising a volatile solvent; and wherein the physiologically active agent and dermal penetration enhancer form an amorphous deposit upon evaporation of the volatile carrier, said amorphous deposit forming a reservoir within the stratum corneum; and (A) wherein the composition has a release rate profile of physiologically active agent so as to provide a ratio of the maximum concentration (Cmax) to the average concentration (Cavg) for the physiologically active agent over the dosage interval within the range of 1 to 10.Type: GrantFiled: December 7, 2004Date of Patent: January 22, 2013Assignee: Acrux DDS Pty Ltd.Inventors: Timothy Matthias Morgan, Nina Frances Wilkins, Kathryn Taci-Jane Klose, Barrie Charles Finnin, Barry Leonard Reed
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Patent number: 8177449Abstract: An implement 1 for applying a volume of liquid to a treatment surface. The implement includes a support 3 onto which is mounted a receptacle 2, the receptacle defining a reservoir space 4 which receives the liquid. The receptacle includes a wall 6 having a working surface that is used to spread the liquid over the treatment surface. The wall 6 is resiliently deformable so in use the working surface maintains contact with the treatment surface when spreading the liquid. The implement has a specific application in applying a transdermal lotion to the axilla area of the user. A system for transdermal administration of a physiological active agent from a liquid composition and a method of conducting the transdermal administration.Type: GrantFiled: February 26, 2007Date of Patent: May 15, 2012Assignee: Acrux DDS Pty Ltd.Inventors: Peter Bayly, Mark Simon Bayly, Magnus Ahlstrom, Adam Charles Watkinson
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Patent number: 8071075Abstract: The invention relates to a method for treatment or prophylaxis of a disease or condition in an animal comprising administering to a mucosal membrane of said animal in need of such treatment a therapeutically effective amount of a drug delivery system comprising at least one physiologically active agent or prodrug thereof and at least one penetration enhancer selected from safe ester sunscreens.Type: GrantFiled: October 5, 2007Date of Patent: December 6, 2011Assignee: Acrux DDS Pty Ltd.Inventors: Barry Leonard Reed, Timothy Matthias Morgan, Barrie Charles Finnin
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Patent number: 7438203Abstract: The invention relates to a method for treatment or prophylaxis of a disease or condition in an animal comprising administering to a mucosal membrane of said animal in need of such treatment a therapeutically effective amount of a drug delivery system comprising at least one physiologically active agent or prodrug thereof and at least one penetration enhancer selected from safe ester sunscreens.Type: GrantFiled: January 20, 2004Date of Patent: October 21, 2008Assignee: Acrux DDS Pty LtdInventors: Barry Lenard Reed, Timothy Matthias Morgan, Barrie Charles Finnin
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Patent number: 7387789Abstract: The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of a non-steroidal anti-inflammatory drug; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one volatile liquid. The invention also provides a method for administering at least one systemic or locally acting non-steroidal anti-inflammatory drug to an animal which comprises applying an effective amount of the non-steroidal anti-inflammatory drug in the form of the drug delivery system of the present invention.Type: GrantFiled: September 8, 2006Date of Patent: June 17, 2008Assignee: ACRUX DDS Pty. Ltd.Inventors: Kathryn Traci-Jane Klose, Margarita Vladislavova Bakalova, Timothy Matthias Morgan, Barrie Charles Finnin, Barry Leonard Reed
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Publication number: 20070293842Abstract: A container includes a receptacle (6) for holding a substance, drug or liquid, and having an opening (7) to the receptacle 6 through which the substance can be dispensed and having a circular and domed spreading surface (15) adjacent the opening for spreading and the accurate delivery of a thin layer of liquid over an area of skin. The container also includes a closure (3) including a cap (4) having a seal or plug (16) for sealing the receptacle (6), and a collar (5) with a cam follower surface (8) rotatable relative to the cap about an axis, whereby rotation of the collar (5) relative to the cap (4) moves the seal in an axial direction away from a seal position.Type: ApplicationFiled: July 14, 2005Publication date: December 20, 2007Applicant: Acrux DDS Pty LtdInventors: Barry Knight, Peter Bayly, Kon Wong, Timothy Morgan
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Patent number: 7094422Abstract: The present invention provides a topical drug delivery system which comprises: a therapeutically effective amount of an antifungal agent; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and a volatile liquid. The invention also provides a method for administering at least one systemic acting antifungal agent to an animal which comprises applying an effective amount of the antifungal agent in the form of the drug delivery system of the present invention.Type: GrantFiled: August 20, 2003Date of Patent: August 22, 2006Assignee: Acrux DDS PTY Ltd.Inventors: Nora Yat Knork Chew, Barry Leonard Reed, Timothy Matthias Morgan, Barrie Charles Finnin
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Publication number: 20060163276Abstract: A substance dispensing device associated with a usage indicator is disclosed. The device includes a substance storage container and a pump operable to dispense substance from the container. The usage indicator includes a movable member that is movable in response to operation of the pump. The movable member includes an indicator providing a visual indication of the extent to which substance has been dispensed from the device.Type: ApplicationFiled: December 22, 2003Publication date: July 27, 2006Applicant: Acrux DDS Pty LtdInventors: Kon Wong, John Oretti
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Patent number: 6998138Abstract: The present invention provides a topical drug delivery system which comprises: a therapeutically effective amount of an anti-alopecia agent; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and a volatile liquid. The invention also provides a method for administering at least one systemic acting anti-alopecia agent to an animal which comprises applying an effective amount of the anti-alopecia agent in the form of the drug delivery system of the present invention.Type: GrantFiled: August 8, 2003Date of Patent: February 14, 2006Assignee: Acrux DDS Pty. Ltd.Inventors: Nora Yat Knork Chew, Barry Leonard Reed, Timothy Matthias Morgan, Barrie Charles Finnin
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Patent number: 6978945Abstract: Hand-held dispensing devices for dispensing and applying a substance to the skin of a host are described. The devices include a hollow body, a capsule mounted within the hollow body for containing the substance, a nozzle mounted within the hollow body communicating with the substance in the capsule, an actuator to cause metered quantities of the substance to be dispensed from the capsule through the nozzle, a shroud defining an exit space for receiving the substance emerging from the nozzle, and a cap detachably mounted on the shroud to selectively open and close the nozzle and thereby control escape of the substance from the capsule.Type: GrantFiled: May 21, 2003Date of Patent: December 27, 2005Assignee: Acrux DDS Pty LtdInventors: Kon Euan Wong, Mark Simon Bayly
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Patent number: 6964777Abstract: The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of an antianxiety agent; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one volatile liquid. The invention also provides a method for administering at least one systemic acting antianxiety agent to an animal which comprises applying an effective amount of the antianxiety agent in the form of the drug delivery system of the present invention.Type: GrantFiled: May 2, 2003Date of Patent: November 15, 2005Assignee: Acrux DDS PTY LTDInventors: Kathryn Traci-Jane Klose, Ennio La Guardia, Timothy Matthias Morgan, Barrie Charles Finnin, Barry Leonard Reed
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Patent number: 6929801Abstract: The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of an antiParkinson agent; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one volatile liquid. The invention also provides a method for administering at least one systemic acting antiParkinson agent to an animal which comprises applying an effective amount of the antiParkinson agent in the form of the drug delivery system of the present invention.Type: GrantFiled: May 2, 2003Date of Patent: August 16, 2005Assignee: Acrux DDS PTY LTDInventors: Kathryn Traci-Jane Klose, Ngan Thi Kim Tran, Timothy Matthias Morgon, Barrie Charles Finnin, Barry Leonard Reed
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Patent number: 6923983Abstract: The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of a hormone; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one volatile liquid.Type: GrantFiled: May 2, 2003Date of Patent: August 2, 2005Assignee: Acrux DDS PTY LTDInventors: Timothy Matthias Morgan, Margarita Vladislavova Bakalova, Karthryn Traci-Jane Klose, Barrie Charles Finnin, Barry Leonard Reed
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Patent number: 6916487Abstract: The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of an antiemetic; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one volatile liquid. The invention also provides a method for administering at least one systemic acting antiemetic thereof to an animal which comprises applying an effective amount of the antiemetic in the form of the drug delivery system of the present invention.Type: GrantFiled: May 2, 2003Date of Patent: July 12, 2005Assignee: Acrux DDS PTY LTDInventors: Kathryn Traci-Jane Klose, Jianwen Zhou, Timothy Matthias Morgan, Barrie Charles Finnin, Barry Leonard Reed
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Patent number: 6916486Abstract: The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of an analgesic; at least one dermal penetration enhancer, which is a safe skin-tolerant ester sunscreen ester; and at least one volatile liquid. The invention also provides a method for administering at least one systemic acting analgesic to an animal which comprises applying an effective amount of the analgesic in the form of the drug delivery system of the present invention.Type: GrantFiled: May 2, 2003Date of Patent: July 12, 2005Assignee: Acrux DDS PTY LTDInventors: Kathryn Traci-Jane Klose, Felicia Maria Colagrande, Timothy Matthias Morgan, Barrie Charles Finnin, Barry Leonard Reed
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Patent number: 6818226Abstract: A transdermal drug delivery system which comprises at least one physiologically active agent or prodrug thereof and at least one dermal penetration enhancer; characterised in that the dermal penetration enhancer is a safe skin-tolerant ester sunscreen.Type: GrantFiled: July 24, 2001Date of Patent: November 16, 2004Assignee: ACRUX DDS Pty. Ltd.Inventors: Barry Leonard Reed, Timothy Matthias Morgan, Barrie Charles Finnin