Patents Assigned to Active Motif, Inc.
  • Patent number: 9938524
    Abstract: The invention provides novel methods and materials for genetic and genomic analysis using single or multiplex isolation of protein-associated nucleic acids, including transposase-assisted chromatin immunoprecipitation (TAM-ChIP) and antibody-oligonucleotide proximity ligation. These methods comprise tagging and isolating chromatin or other protein-associated nucleic acids and using antibody-oligonucleotide complexes that recognize the proteins associated with such nucleic acids.
    Type: Grant
    Filed: November 23, 2012
    Date of Patent: April 10, 2018
    Assignee: Active Motif, Inc.
    Inventors: Joseph Fernandez, Mary Anne Jelinek, Brian Stanley Egan
  • Publication number: 20180010121
    Abstract: Disclosed herein are compositions, methods and kits useful for epigenetic analysis based on the use of transposons that are targeted to specific regions of chromatin based on DNA-DNA interactions, protein-protein interactions, RNA-RNA interactions, and nucleic acid-protein interactions.
    Type: Application
    Filed: May 22, 2014
    Publication date: January 11, 2018
    Applicant: Active Motif, Inc.
    Inventors: Mary Anne Jelinek, Brian Stanley Egan, Joseph Fernandez
  • Publication number: 20160115474
    Abstract: Disclosed herein are compositions, methods and kits useful for epigenetic analysis based on the use of transposons that are targeted to specific regions of chromatin based on DNA-DNA interactions, protein-protein interactions, RNA-RNA interactions, and nucleic acid-protein interactions.
    Type: Application
    Filed: May 22, 2014
    Publication date: April 28, 2016
    Applicant: Active Motif, Inc.
    Inventors: Mary Anne Jelinek, Brian Stanley Egan, Joseph Fernandez