Abstract: Methods and compositions for reducing and/or inhibiting inflammation by topical application of dermatocosmetic compositions comprising effective amounts of extracts of Coriolus versicolor that have been hydrolyzed by an acid protease, preferably Rhizomucor miehei, and thereafter rendered substantially devoid of acid-protease activity.
Type:
Grant
Filed:
December 14, 2011
Date of Patent:
June 23, 2015
Assignee:
Active Organics, Inc.
Inventors:
Michael Bishop, Elysiann Bishop, Walter Smith, Glen Gillis
Abstract: Topical compositions comprising extracts of Rhizomucor miehei that are substantially devoid of acid-protease activity and their use in treating dermatologic conditions, including reducing the appearance of signs of skin aging.
Type:
Grant
Filed:
February 15, 2012
Date of Patent:
July 24, 2012
Assignee:
Active Organics, Inc.
Inventors:
Michael Bishop, Elysiann Bishop, Glen Gillis
Abstract: Topical compositions comprising extracts of Rhizomucor miehei that are substantially devoid of acid-protease activity and their use in treating dermatologic conditions, including reducing the appearance of signs of skin aging.
Type:
Grant
Filed:
June 3, 2010
Date of Patent:
March 27, 2012
Assignee:
Active Organics, Inc.
Inventors:
Michael Bishop, Elysiann Bishop, Glen Gillis
Abstract: Methods and compositions for reducing and/or inhibiting inflammation by topical application of dermatocosmetic compositions comprising effective amounts of extracts of Coriolus versicolor that have been hydrolyzed by an acid protease, preferably Rhizomucor miehei, and thereafter rendered substantially devoid of acid-protease activity.
Type:
Application
Filed:
November 11, 2010
Publication date:
June 2, 2011
Applicant:
Active Organics, Inc.
Inventors:
Michael Bishop, Elysiann Bishop, Walter Smith, Glen Gillis
Abstract: Methods and compositions for reducing and/or inhibiting inflammation by topical application of dermatocosmetic compositions comprising effective amounts of extracts of Coriolus versicolor that have been hydrolyzed by an acid protease, preferably Rhizomucor miehei, and thereafter rendered substantially devoid of acid-protease activity.
Type:
Grant
Filed:
January 14, 2008
Date of Patent:
December 21, 2010
Assignee:
Active Organics, Inc.
Inventors:
Michael Bishop, Elysiann Bishop, Walter Smith, Glen Gillis
Abstract: Novel compositions comprising one or more of an acid protease and an acidic buffer, the acidic buffer comprising an acid and a pharmaceutically or cosmetically acceptable carrier, vehicle or excipient, useful for treating or preventing abnormal biological conditions, diseases or disorders, and/or for improving the texture or appearance of the skin, and/or for enhancing epidermal exfoliation and/or for enhancing epidermal cell renewal and to methods for the use of the compositions. The acid protease comprises one or more proteolytic enzymes which exhibit proteolytic activity at pH values below that of the surface of the skin, i.e., approximately pH 5.5. The acidic buffer comprises inorganic and/or organic acids or mixtures thereof with a pharmaceutically or cosmetically acceptable carrier, vehicle or excipient. The buffer is capable of reducing the pH of the surface of the skin to less than pH 5.5 and is susceptible to neutralization by normal epidermal processes.
Type:
Grant
Filed:
June 13, 1996
Date of Patent:
November 2, 1999
Assignee:
Active Organics, Inc.
Inventors:
Scott J. Norton, Michael A. Bishop, Glen S. Gillis