Patents Assigned to ACTUATE THERAPEUTICS INC.
  • Methods of treating malignant lymphoproliferative disorders
    Patent number: 11980607
    Abstract: Methods of treating malignant lymphoproliferative disorders in a patient, comprising administering an effective amount of a GSK-3? inhibitor, for example 9-ING-41, are provided. Also provided are methods for treating malignant lymphoproliferative disorders comprising administering a GSK-3? inhibitor, for example 9-ING-41, in combination with a second or multiple therapeutic agents.
    Type: Grant
    Filed: November 3, 2022
    Date of Patent: May 14, 2024
    Assignee: ACTUATE THERAPEUTICS INC.
    Inventors: Francis Giles, Andrew Mazar
  • Methods of treating malignant lymphoproliferative disorders
    Patent number: 11510904
    Abstract: Methods of treating malignant lymphoproliferative disorders in a patient, comprising administering an effective amount of a GSK-3? inhibitor, for example 9-ING-41, are provided. Also provided are methods for treating malignant lymphoproliferative disorders comprising administering a ({umlaut over (?)}8K-3? inhibitor, for example 9-ING-41, in combination with a second or multiple therapeutic agents.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: November 29, 2022
    Assignee: ACTUATE THERAPEUTICS INC.
    Inventors: Francis Giles, Andrew Mazar
  • Solid forms of 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione
    Patent number: 11407759
    Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl) pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: August 9, 2022
    Assignee: Actuate Therapeutics Inc.
    Inventor: Yamin Zhang
  • Solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione
    Patent number: 11136334
    Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: October 5, 2021
    Assignee: ACTUATE THERAPEUTICS INC.
    Inventor: Yamin Zhang