Patents Assigned to ADAERATA, LIMITED PARTNERSHP
  • Single domain antibodies as inhibitors of PCSK9
    Patent number: 9879093
    Abstract: Antibodies (e.g., sdAbs) binding to PCSK9 are described. Nucleic acids encoding such Abs, host cells expressing such Abs and pharmaceutical composition comprising same are described. The use of these PCSK9-binding Abs for lowering low-density lipoprotein-cholesterol (LDL-C) levels and for the treatment of cardiovascular disorders, is also described.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 30, 2018
    Assignees: ADAERATA, LIMITED PARTNERSHP, NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Nabil G. Seidah, Jianbing Zhang