Abstract: A method of cooling a material including the steps of (i) providing a cryotherapy instrument, (ii) positioning a portion of the cryotherapy instrument adjacent the material to be cooled, and (iii) circulating a cryogenic fluid through the cryotherapy instrument under physical conditions near a critical point of a liquid-vapor system for the cryogenic fluid. The critical point defines a point in a phase diagram of the liquid-vapor system where molar volumes are substantially equivalent for liquid and gas, whereby vapor lock associated with cooling of the cryotherapy instrument is avoided.
Type:
Grant
Filed:
November 22, 2013
Date of Patent:
August 9, 2016
Assignee:
ADAGIO MEDICAL, INC.
Inventors:
Peter J. Littrup, Alexei V. Babkin, Robert V. Duncan, Pramod Kerkar, Sergey T. Boldarev
Abstract: An endovascular near critical fluid based cryoablation catheter for creating an elongated lengthwise-continuous lesion in tissue can comprise an elongated shaft, a flexible distal tissue treatment section, and a distal tip. A plurality of flexible tubes can extend through the distal treatment section to transport a near critical fluid to and from the distal tip. The distal treatment section can also include a flexible fluid-sealed cover or barrier layer surrounding the delivery tubes. The cover and tubes can collectively define a space which is filled with a fluidic thermally conductive media. The thermally conductive media, fluid delivery tubes, and the cover can be arranged such that a flow of the near critical fluid through the tube bundle transfers heat between a target tissue and the distal treatment section of the catheter thereby creating the elongated lengthwise-continuous lesion in the tissue.
Type:
Application
Filed:
September 22, 2014
Publication date:
August 4, 2016
Applicant:
Adagio Medical, Inc.
Inventors:
Alexei V. Babkin, Steven W. Kovalcheck, Xiaoyu Yu
Abstract: Apparatus, systems and methods for creation of ablation lesions for the treatment of atrial fibrillation. A method for creating a maze of lesions to isolate macro re-entrant circuits. An ablation catheter with at least one ablation surface at its distal end. A flexible ablation probe with at least one ablation surface at its distal end. A clamp with opposing jaws having at least one jaw with an ablation surface, optionally including temperature sensing.