Patents Assigned to Adamantech, Inc.
  • Patent number: 4917930
    Abstract: Compositions having enhanced gas and drug transporting capability, are prepared by providing a perfluoro compound dispersed in an aqueous medium with a surfactant to form an aqueous initial dispersion, concentrating the perfluoro compound phase of the dispersion as by centrifugation or filtration, wherein a portion of the surfactant remains complexed with the particles of the perfluoro compound phase and the balance of the surfactant is in the aqueous phase, separating the phases, and redispersing the particles of the concentrated perfluoro compound phase to form a final dispersion in which greater than 65% by weight, and preferably at least 75%, of the surfactant present is complexed with the perfluoro compound particles.
    Type: Grant
    Filed: October 3, 1986
    Date of Patent: April 17, 1990
    Assignee: Adamantech, Inc.
    Inventor: William McCormick
  • Patent number: 4889525
    Abstract: Method of sensitizing hypoxic tumor cells to radiotherapy and chemotherapy by contacting the cells or the vasculature thereof with an aqueous dispersion of an oxygen carrying perfluoro compound and a dispersant for the compound, and sensitizing chemotherapeutic and protective compositions therefor.
    Type: Grant
    Filed: January 11, 1988
    Date of Patent: December 26, 1989
    Assignee: Adamantech, Inc.
    Inventors: John M. Yuhas, Robert L. Goodman, Robert E. Moore
  • Patent number: 4879062
    Abstract: An inert, water-immiscible inert organic liquid having gas transport properties, water and a suitable emulsifying agent are formed into a stable gel by emulsifying a mixture of the same, concentrating the emulsion to form a gel phase and a liquid phase and separating the two phases. The resulting gel can be used as an ointment or cosmetic for skin irritations or wounds, or as a coating in industrial applications where extended contact of a surface with a gas, such as oxygen, is desired. Fluorocarbons or low viscosity silicone oils are suitable organic liquid components of the gels.
    Type: Grant
    Filed: September 19, 1985
    Date of Patent: November 7, 1989
    Assignee: Adamantech, Inc.
    Inventor: Robert E. Moore
  • Patent number: 4766261
    Abstract: Fluorocarbons are purified and toxicity substantially reduced by contact with a substantially dry, strongly basic and strongly nucleophilic alkali or alkaline earth metal compound, and separating the decomposition products which form.
    Type: Grant
    Filed: December 10, 1985
    Date of Patent: August 23, 1988
    Assignee: Adamantech, Inc.
    Inventor: Thomas W. Bierl
  • Patent number: 4742050
    Abstract: Method of sensitizing hypoxic tumor cells to radiotherapy and chemotherapy by contacting the cells or the vasculature thereof with an aqueous dispersion of an oxygen carrying perfluoro compound and a dispersant for the compound, and sensitizing chemotherapeutic and protective compositions therefor.
    Type: Grant
    Filed: September 9, 1987
    Date of Patent: May 3, 1988
    Assignee: Adamantech, Inc.
    Inventors: John M. Yuhas, deceased, Robert L. Goodman, Robert E. Moore
  • Patent number: 4640833
    Abstract: Method of X-raying animals using as a contrast agent a perfluorobromoalkyl ether of the formula C.sub.m F.sub.2m+1 OC.sub.n F.sub.2n Br where m and n independently are integers of from 2 to 6, wherein the ether is used either neat or in an aqueous dispersion such as an emulsion.
    Type: Grant
    Filed: March 11, 1985
    Date of Patent: February 3, 1987
    Assignees: Adamantech, Inc., Children's Hospital Research Foundation
    Inventors: Christ Tamborski, Leland C. Clark, Jr.
  • Patent number: 4569784
    Abstract: An inert, water-immiscible inert organic liquid having gas transport properties, water and a suitable emulsifying agent are formed into a stable gel by emulsifying a mixture of the same, concentrating the emulsion to form a gel phase and a liquid phase, and separating the two phases. The resulting gel can be used as an ointment or cosmetic for skin irritations or wounds, or as a coating in industrial applications where extended contact of a surface with a gas, such as oxygen, is desired. Fluorocarbons or low viscosity silicone oils are suitable organic liquid components of the gels.
    Type: Grant
    Filed: October 20, 1981
    Date of Patent: February 11, 1986
    Assignee: Adamantech, Inc.
    Inventor: Robert E. Moore