Abstract: Embodiments of the present invention provide a topical agent that is a preparation containing hydrolyzed silk. The topical agent is applied to a wound site for use in wound healing, an thus, an object thereof being to have an effect of promoting wound healing and to satisfy practical application conditions with regard to an irritative property, stability, handling ease, and the like. The topical agent contains hydrolyzed fibroin, an oil-based component, and a water-based component. The topical agent according to the embodiments of the present invention is preferably an ointment or a cream. The topical agent contains hydrolyzed fibroin as an active ingredient in an amount of 1 to 40 wt %, and preferably does not contain a surfactant.