Abstract: A method for linking a natural product and gene cluster is disclosed. In some embodiments, monomers of natural products are predicted from a gene sequence. In other embodiments, monomers of natural products are predicted from a chemical structure of a natural product. In another embodiment, monomers predicted from gene sequences are aligned with monomers predicted from chemical structures.
Type:
Grant
Filed:
December 14, 2016
Date of Patent:
December 12, 2023
Assignee:
Adapsyn Bioscience Inc.
Inventors:
Nishanth Merwin, Chris DeJong, Chad Johnston, Gregory Chen, Haoxin Li, Michael Skinnider, McLean Edwards, Nathan Magarvey, Phil Rees