Abstract: The present invention provides a tri-arm star bottlebrush polymer or copolymer that can be photocrosslinked to form a solvent free soft and optically clear elastomeric gel with a specific refractive index and Young's Modulus, making it suitable for implantation and for use as an accommodating intraocular lens (IOL), a pseudoaccomodating, presbyopia correcting IOL, or a custom-molded IOL. In various embodiments, the tri-arm star bottlebrush polymer is formed using a trifunctional reversible addition fragmentation chain-transfer (RAFT) agent and will have three methacrylate and/or acrylate polymer chains extending therefrom. These methacrylate polymer chains comprising the polymerized residues of a methacrylate macromonomer and one or more hydroxy-functionalized methacrylate chain extenders with alkene functional groups covalently bonded thereto.

Abstract: A device and method for forming an adaptive optic in the capsule of a human eye is disclosed, comprising a capsular interface enclosing an optically acceptable medium. The device establishes a physiologic range of optical power in response to a range of ciliary contractile states. The preferred bi-phasic medium of the device is comprised of a solid three dimensional polymeric network suspended in a liquid aqueous phase and bonded to a capsular interface. The polymeric network provides shape to the capsular interface, optical power, and a physiologic response to the suspensory ligament. The three dimensional network of the bi-phasic medium mimics the stacked fiber configuration and elasticity of a natural lens. An alternative embodiment utilizing a single phase medium is also disclosed with associated structural features provided in the capsular interface.

Abstract: A device and method for forming an adaptive optic in the capsule of a human eye is disclosed, comprising a capsular interface enclosing an optically acceptable medium. The device establishes a physiologic range of optical power in response to a range of ciliary contractile states.