Patents Assigned to Addex Pharmaceuticals SA
  • NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS
    Publication number: 20090124625
    Abstract: The present invention relates to novel compounds of formula (I) wherein W, n, X and W? are defined in the description; invention compounds are modulators of metabotropic glutamate receptors—subtype 5 (“mGluR5”) which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.
    Type: Application
    Filed: June 17, 2005
    Publication date: May 14, 2009
    Applicant: Addex Pharmaceuticals SA
    Inventors: Anne-Sophie Bessis, Christelle Bolea, Beatrice Bonnet, Mark Epping-Jordan, Nicolas Poirier, Sonia-Maria Poli, Jean-Philippe Rocher, Yves Thollon
  • Novel aminopyridine derivatives as mGluR5 antagonists
    Publication number: 20080004316
    Abstract: The invention relates to novel aminopyridine derivatives of formula (I) wherein R1 is methyl an R4 and amino group —NR6R7 and R5 forms an arylalkynyl- or heteroarylalkynyl-group. The compounds are useful in the prevention or treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.
    Type: Application
    Filed: March 13, 2007
    Publication date: January 3, 2008
    Applicant: Addex Pharmaceuticals SA
    Inventors: Christelle Bolea, Vincent Mutel, Jean-Philippe Rocher, Anne-Sophie Bessis, Emmanuel Le Poul
  • Aminopyridine derivatives as mGluR5 antagonists
    Patent number: 7205411
    Abstract: The invention relates to novel aminopyridine derivatives of formula (I) wherein R1 is methyl an R4 and amino group —NR6R7 and R5 forms an arylalkynyl- or heteroarylalkynyl-group.
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: April 17, 2007
    Assignee: Addex Pharmaceuticals SA
    Inventors: Christelle Bolea, Vincent Mutel, Jean-Philippe Rocher, Anne-Sophie Bessis, Emmanuel Le Poul
  • Novel aminopyridine derivatives as mGluR5 antagonists
    Publication number: 20060030601
    Abstract: The invention relates to novel aminopyridine derivatives of formula (I) wherein R1 is methyl an R4 and amino group —NR6R7 and R5 forms an arylalkynyl- or heteroarylalkynyl-group. The compounds are useful in the prevention or treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.
    Type: Application
    Filed: September 2, 2005
    Publication date: February 9, 2006
    Applicant: Addex Pharmaceuticals SA
    Inventors: Christelle Bolea, Vincent Mutel, Jean-Philippe Rocher, Anne-Sophie Bessis, Emmanuel Le Poul