Abstract: A method is provided for treating warm-blooded animals so as to reduce their voluntary alcohol consumption comprising the administration to the animals of an angiotensin converting enzyme inhibitor.

Abstract: A method of use of an angiotensin converting enzyme inhibitor is provided which comprises administration of the inhibitor to warm-blooded animals so as to reduce their voluntary alcohol consumption. The method further includes combining the use of opiate receptor antagonist to further reduce alcohol consumption.

Abstract: The present invention relates to a simultaneous matched feeding apparatus. The apparatus includes two tube-like members containing liquids. The upper portions of the tubes are interconnected to allow air pressure in the upper portions of the tubes to equilibrate such that when one liquid is removed from one of the tubes, the other tube automatically dispenses a corresponding amount of another liquid.

Abstract: Novel opioid compounds are provided having a phenolic hydroxyl and a pentet of alternating basic hydrophilic and hydrophobic groups derived from basic amino acids and hydrophobic amino acids. Desirably, the pentet, usually sextet, is separated from the phenolic ring by at least about 3 atoms in a chain, preferably at least about 15 atoms in a chain and not more than about 30 atoms in a chain (for rings one will take the average of the shortest and longest distances). Particularly, a polypeptide is provided having tyrosyl at the amine end, desirably as the first amino acid of leu- or met-enkephalin and a sextet of alternating basic hydrophilic and hydrophobic amino acids spaced from the enkephalin by at least about one amino acid. Desirably, the polypeptide is at least 1,200 molecular weight and under about 2,500 molecular weight.

Abstract: Apparatus is provided in which a signal indicative of the tremor is sensed. This signal is amplified in a variable gain amplifier. During an initial time interval the size of the amplifier signal is determined and the gain of the amplifier is adjusted in response to the signal size. Then means are provided for indicating the size of frequency of the adjusted signal during a further time period to give a tremor measurement which may be relatively easily interpreted.