Patents Assigned to ADIR
  • Publication number: 20100013112
    Abstract: A system and method for managing water content in a fluid include a collection chamber for collecting water from the fluid with a desiccant, and a regeneration chamber for collecting water from the desiccant and transferring it to a second fluid. An evaporator cools the desiccant entering the collection chamber, and a condenser heats the desiccant entering the regeneration chamber. Diluted desiccant from the collection chamber is exchanged with concentrated desiccant from the regeneration chamber in such a way as to efficiently control the transfer of both mass and heat between the chambers. In one embodiment, mass is not exchanged until one or both of the desiccant levels in the chambers exceeds a predetermined level. Heat is transferred between the two desiccant flows as they are transferred between the chambers. This increases efficiency and reduces the energy input required for the evaporator and the condenser.
    Type: Application
    Filed: August 27, 2007
    Publication date: January 21, 2010
    Applicant: ADIR SEGAL, LTD
    Inventor: Dan Forkosh
  • Publication number: 20090277264
    Abstract: An assembly for measuring both the level and specific gravity of a liquid in a container includes a first sensor arrangement for sensing the level of the liquid in the container, and a second sensor arrangement for sensing the specific gravity of the liquid. The first sensor arrangement measures and then independently outputs at least one signal relating to the liquid level in the container. The second sensor arrangement measures and then independently outputs at least one signal relating to the specific gravity of the liquid in the container, thereby providing an integrated device to measure both parameters of the liquid.
    Type: Application
    Filed: August 24, 2007
    Publication date: November 12, 2009
    Applicant: ADIR SEGAL, LTD.
    Inventor: Dan Forkosh
  • Publication number: 20080307802
    Abstract: A system and method for managing water content in a fluid includes a collection chamber for collecting water from the fluid with a desiccant, and a regeneration chamber for collecting water from the desiccant and transferring it to a second fluid. An evaporator cools the desiccant entering the collection chamber, and a second evaporator cools the second fluid to extract the water. The evaporators use a refrigerant, the flow of which is controlled by a flow control valve. When the temperature in the second evaporator drops below a set point, the refrigerant flow to the second evaporator is stopped, and the refrigerant flow to the first evaporator is increased. This increases the water collection in the collection chamber, and causes a rise in the temperature in the second evaporator. The valve is then opened to increase the cooling in the second evaporator.
    Type: Application
    Filed: December 7, 2006
    Publication date: December 18, 2008
    Applicant: ADIR SEGAL, LTD.
    Inventor: Dan Forkosh
  • Publication number: 20020161228
    Abstract: A compound selected from those of formula (I): 1
    Type: Application
    Filed: March 25, 2002
    Publication date: October 31, 2002
    Applicant: ADIR ET COMPAGNIE
    Inventors: Jean Louis Peglion, Aimee Dessinges, Christophe Poitevin, Mark Millan, Anne Dekeyne
  • Publication number: 20020052400
    Abstract: The invention relates to compounds of formula (I): 1
    Type: Application
    Filed: August 28, 2001
    Publication date: May 2, 2002
    Applicant: ADIR ET COMPAGNIE
    Inventors: Gerald Guillaumet, Marie-Claude Viaud, Ahmed Mamai, Isabelle Charton, Pierre Renard, Caroline Bennejean, Beatrice Guardiola, Philippe Daubos
  • Publication number: 20020040036
    Abstract: The invention relates to a compound of formula (I): 1
    Type: Application
    Filed: September 25, 2001
    Publication date: April 4, 2002
    Applicant: ADIR ET COMPAGNIE
    Inventors: Otto Meth-Cohn, Chu-Yi Yu, Pierre Lestage, Marie-Cecile Lebrun, Daniel-Henri Caignard, Pierre Renard
  • Publication number: 20020035123
    Abstract: The invention relates to a compound of formula (I): 1
    Type: Application
    Filed: September 25, 2001
    Publication date: March 21, 2002
    Applicant: ADIR ET COMPAGNIE
    Inventors: Otto Meth-Cohn, Chu-Yi Yu, Pierre Lestage, Marie-Cecile Lebrun, Daniel-Henri Caignard, Pierre Renard
  • Patent number: 6350759
    Abstract: Compound of formula (I): wherein: R1 represents hydrogen or wherein A is as defined in the description, R2 and R3 each independently represents alkyl, cycloalkyl, heterocycloalkyl, optionally substituted aryl, optionally substituted heteroaryl, cycloalkylalkyl, heterocycloalkylalkyl, optionally substituted arylalkyl, optionally substituted heteroarylalkyl,or optionally substituted aminoalkyl or R2 and R3, together with the carbon atom carrying them, form cycloalkyl or monocyclic heterocyclic group, substituted or unsubstituted, R40 represents hydrogen or a group selected from optionally substituted alkyl, optionally substituted alkenyl and optionally substituted alkynyl or Q or —V—Q wherein V represents alkylene, alkenylene or alkynylene and Q represents optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocycloalkyl,or optionally substituted heteroaryl, R41 and R5 together form a bond or each represents hydrogen, R6,
    Type: Grant
    Filed: October 22, 1999
    Date of Patent: February 26, 2002
    Assignee: Adir et Compagnie
    Inventors: Patrick Casara, Gilbert Dorey, Pierre Lestage, Brian Lockhart
  • Patent number: 6339092
    Abstract: A compound selected from those of the formula (I): wherein: R1 represents hydrogen or halogen, or alkyl or alkoxy, R2 represents hydroxy, alkoxy or —NHOH, Ar1 represents phenylene or biphenylene, X represents oxygen or sulphur, NR, —C≡C— or a bond, R represents hydrogen or alkyl, n is an integer from 0 to 6 inclusive, Ar2 represents any one of the groups as defined in the description, its isomers and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same which are useful as metalloprotease inhibitors.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: January 15, 2002
    Assignee: Adir et Compagnie
    Inventors: Guillaume de Nanteuil, Alain Benoist, Jacqueline Bonnet, Massimo Sabatini, Ghanem Atassi, Alain Pierre
  • Patent number: 6326377
    Abstract: Compounds of formula (I): wherein: m is 0 to 3 inclusive, n is 0 to 3 and 2≦m+n≦3, p is 1 to 6 inclusive, X represents cyano or —CO—NR4R5, R4 and R5 being selected from hydrogen, linear or branched (C1-C6)-alkyl, (C3-C7)-cycloalkyl,and aryl, R1 and R2 each independently represent hydrogen or linear or branched (C1-C6)-alkyl, R3 represents hydrogen, optionally substituted phenyl, naphthyl or heteroaryl, or aryloxy or arylthio, or aryl or heteroaryl substituted by A′—Cy, A′ and Cy being as defined in the description, and medicinal products containing the same which are useful as D3 receptor ligands.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: December 4, 2001
    Assignee: Adir et Compagnie
    Inventors: Gilbert Lavielle, Thierry Dubuffet, Patrick Hautefaye, Françoise Lejeune, Mark Millan
  • Patent number: 6323222
    Abstract: Compound of formula (I): wherein: n represents 0 or 1, R1 represents hydrogen, arylalkyl, alkyl, acyl, alkoxycarbonyl, arylalkoxycarbonyl or trifluoroacetyl, R2 represents alkyl, X represents oxygen, chlorine, OR3, SR4 or NOR5, R3 represents hydrogen, alkyl, acyl, alkoxycarbonyl or arylalkoxycarbonyl, R4 represents hydrogen, alkyl or aryl, R5 represents hydrogen or optionally substituted alkyl, represents a single or double bond, Ar represents aryl or heteroaryl, its isomers and addition salts thereof with a pharmaceutically acceptable acid, and medicinal products containing the same which are useful as facilitators of memory and cognition and antalgic agents.
    Type: Grant
    Filed: May 2, 2000
    Date of Patent: November 27, 2001
    Assignee: Adir et Compagnie
    Inventors: Sylvain Rault, Olivier Renault, Jean Guillon, Patrick Dallemagne, Pierre Renard, Bruno Pfeiffer, Pierre Lestage, Marie-Cécile Lebrun
  • Patent number: 6323220
    Abstract: The invention relates to a compound of formula (I): wherein: A represents pyridine, pyridinium or piperidine R1, R2, R3 and R4 are as defined in the description R5 represents hydrogen, a nitrogen-containing heterocycle or a group of R6 represents hydrogen or linear or branched (C1-C6)alkyl. and medicinal products containing the same which are useful in treating pain or deficiencies in memory.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: November 27, 2001
    Assignee: Adir et Compagnie
    Inventors: Otto Meth-Cohn, Chu-Yi Yu, Pierre Lestage, Marie-Cécile Lebrun, Daniel-Henri Caignard, Pierre Renard
  • Patent number: 6323217
    Abstract: A compound of formula (I): wherein: R1 represents hydrogen or alkyl, R2a and R2b represent a group selected from hydrogen, halogen, alkyl, hydroxy, alkoxy, trihaloalkyl, cyano, nitro, amino, alkylamino and dialkylamino, R3 represents hydrogen or hydroxy, X represents oxygen or methylene, V represents an alkylene chain that is optionally unsaturated and optionally substituted, U represents a bond or an alkylene chain, W represents a group selected from aryl and heteroaryl, each of those groups being optionally substituted by one or more identical or different groups, its isomers, its hydrates, its solvates and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in the treatment of diseases or pathological conditions in which endothelial dysfunction is known.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: November 27, 2001
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Aimée Dessinges, Christophe Poitevin, Jean-Paul Vilaine, Nicole Villeneuve, Catherine Thollon, Marie-Pierre Bourguignon
  • Patent number: 6320058
    Abstract: Process for the industrial synthesis of isoindoline by catalytic hydrogenation of phthalonitrile, and its application in the synthesis of 2-(S)-benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)-butyric acid, its pharmaceutically acceptable salts and its hydrates.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: November 20, 2001
    Assignee: Adir et Compagnie
    Inventors: Jean-Claude Souvie, Claude Fugier, Jean-Pierre Lecouve
  • Patent number: 6319520
    Abstract: The present invention relates to a new solid controlled-release pharmaceutical composition obtained by thermoforming, in the hot state, a mixture based on polymers belonging to the polymethacrylate family and medicinal active ingredient(s).
    Type: Grant
    Filed: June 27, 2000
    Date of Patent: November 20, 2001
    Assignee: Adir et Compagnie
    Inventors: Patrick Wuthrich, Hervé Rolland, Gilles Briault, Gérald Pichon, François Tharrault
  • Patent number: 6319930
    Abstract: The invention relates to compounds of formula (I): A—G1—Cy—G2—Cy—G3—B  (I) wherein: A represents NR1C(Q)R2, C(Q)NR2R3 or NR1C(Q)NR2R3, B represents NR1C(Q)R2, C(Q)NR2R3, NR1C(Q)NR2R3, C(Q)OR1, NR1C(Q)OR2 or NR2R3, G1 and G3 represent an optionally substituted alkylene chain, Cy represents a ring structure and G2 represents a chain and medicinal products containing the same which are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: November 20, 2001
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Carole Descamps-Francois, François Lefoulon, Gérald Guillaumet, Marie-Claude Viaud, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Patent number: 6313160
    Abstract: The invention relates to compounds of formula (I): wherein: R1, R2 and R3 are as defined in the description, X is as defined in the description, Y represents an oxygen atom, a sulphur atom, a C(H)q group, SO or SO2, n is equal to from 0 to 5, A represents a NR5R6 group, and medicinal products containing the same which are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: November 6, 2001
    Assignee: Adir et Compagnie
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Ahmed Mamai, Isabelle Charton, Pierre Renard, Caroline Bennejean, Béatrice Guardiola, Philippe Daubos
  • Patent number: 6310074
    Abstract: The invention relates to compound of formula (I): A—G1—Cy—G2—Cy′—G3—B  (I) wherein: A represents a grouping NR1C(Q)R2, C(Q)NR2R3 or NR1C(Q)NR2R3, B represents a grouping NR1C(Q)R2, NR1C(Q)NR2R3, C(Q)NR2R3, C(Q)OR1, NR1C(Q)OR2 or NR2R3, G1 and G3 represent an optionally substituted alkylene chain, Cy and Cy′, which are different, represent a ring structure or G2 represents a chain and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: October 30, 2001
    Assignee: Adir et Compagnie
    Inventors: Patrick Depreux, Said Yous, Gwenael Cheve, Gérald Guillaumet, Marie-Claude Viaud, Carlos Larraya, Caroline Bennejean, Philippe Delagrange, Pierre Renard, Carole Descamps-Francois
  • Patent number: 6307068
    Abstract: The invention relates to compound of the general formula (I): R—O—A  (I) wherein: R represents the radical of formula (II): A is as defined in the description, and medicinal products containing the same which are useful in treating or in preventing cancer.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: October 23, 2001
    Assignee: Adir et Compagnie
    Inventors: Ying Li, Feng Shan, Jin Ming Wu, Guangshao Wu, Jian Ding, Jianxian Han, Ghanem Atassi, Pierre Renard
  • Patent number: 6302837
    Abstract: A compound selected from those of formula (I): wherein: X represents oxygen, sulphur, or NR3 wherein R3 is as defined in the description, Y represents oxygen, sulphur, NR3, or may represent single bond in certain cases, T represents nitrogen, carbon, or CH, A represents single bond, alkylene, arylene, cycloalkylene, heterocycloalkylene, heteroarylene, or —SO2—R4— wherein R4 is as defined in the description, W represents hydroxy, alkoxy, aryloxy, arylalkoxy, cycloalkyloxy, heterocycloalkyloxy or heteroaryloxy, or hydroxyamino, U1 represents hetero, or alkylene wherein one or more of carbon may optionally be replaced by one or more hetero atoms, V1 represents arylene, heteroarylene,or heterocycloalkylene, U2 represents single bond, hetero or alkylene wherein one or more carbon may optionally be replaced by one or more hetero atoms, V2 represents aryl, heteroaryl, or heterocycloalkyl, Ra, Rb, Rc, which may be identical or different, each independently of the others r
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: October 16, 2001
    Assignee: Adir et Compagnie
    Inventors: Guillaume De Nanteuil, Christine Lila, Tony Verbeuren, Alain Rupin