Abstract: The present invention relates to novel glucofuranose esters and glucopyranose esters of alkyl-fumarates. The esters are suitable for use as active substances in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders.
Abstract: The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.
Type:
Application
Filed:
October 7, 2005
Publication date:
December 10, 2009
Applicant:
ADITECH PHARMA AB
Inventors:
Henrik Nilsson, Florian Schoenharting, Bernd W. Mueller, Joseph R. Robinson, Bonna Robinson
Abstract: The present invention relates to compositions, kits and methods for administration of a first component of fumaric acid ester(s), or a pharmaceutically acceptable salt thereof, and a second component which is a substance that reduces or eliminates flushing.
Abstract: The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designed to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.
Abstract: The present invention relates to novel amino acid salts of fumaric acid monoalkylesters. The salts are suitable for use as active substances in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders.
Type:
Application
Filed:
July 7, 2006
Publication date:
September 18, 2008
Applicant:
ADITECH PHARMA AB
Inventors:
Henrik Nilsson, Jens E.T. Andersen, Bernd W. Mueller
Abstract: The present invention relates to novel strontium salts of fumaric acid monoalkylesters. The salts are suitable for use as active substances in the treatment of e.g.
Type:
Application
Filed:
November 9, 2005
Publication date:
January 3, 2008
Applicant:
ADITECH PHARMA AB
Inventors:
Henrik Nilsson, Jens Andersen, Bernd Mueller, Joseph Robinson, Bonna Robinson