Abstract: The invention relates to oligonucleotides including at least one FANA substituted nucleotide analog and a pyrimidine-purine dinucleotide. The invention also relates to pharmaceutical compositions and methods of use thereof.
Type:
Grant
Filed:
September 29, 2008
Date of Patent:
November 17, 2015
Assignee:
AdiutTide Pharmaceuticals GmbH
Inventors:
Eugen Uhlmann, Harald Debelak, Marion Jurk, Markus Weber