Patents Assigned to ADMA BIOLOGICS, INC.
-
Publication number: 20220023339Abstract: The present invention relates to compositions and methods for the treatment of infection caused by Streptococcus pneumonia. In particular, the invention provides human hyperimmune globulin and compositions thereof for preventing or treating pneumococcal infection. The invention provides methods of producing hyperimmune globulin containing high titers of opsonophagocytic anti-pneumococcal antibodies, compositions containing same, and methods of using the compositions for the prevention and treatment of pneumococcal infection. The invention further provides methods of preventing or treating pneumococcal infection (e.g., upper respiratory infections (e.g., bronchitis, otitis, sinusitis, etc.)) in immunocompromised subjects via administration of hyperimmune globulin compositions of the invention (e.g., containing a high titer of opsonophagocytic anti-pneumococcal antibodies) to immunocompromised subjects.Type: ApplicationFiled: August 9, 2021Publication date: January 27, 2022Applicant: ADMA Biologics, Inc.Inventors: James Mond, Adam S. Grossman
-
Patent number: 11084870Abstract: The present invention relates to compositions and methods for the treatment of infection caused by Streptococcus pneumonia. In particular, the invention provides human hyperimmune globulin and compositions thereof for preventing or treating pneumococcal infection. The invention provides methods of producing hyperimmune globulin containing high titers of opsonophagocytic anti-pneumococcal antibodies, compositions containing same, and methods of using the compositions for the prevention and treatment of pneumococcal infection. The invention further provides methods of preventing or treating pneumococcal infection (e.g., upper respiratory infections (e.g., bronchitis, otitis, sinusitis, etc.)) in immunocompromised subjects via administration of hyperimmune globulin compositions of the invention (e.g., containing a high titer of opsonophagocytic anti-pneumococcal antibodies) to immunocompromised subjects.Type: GrantFiled: April 15, 2019Date of Patent: August 10, 2021Assignee: ADMA BIOLOGICS, INC.Inventors: James Mond, Adam S. Grossman
-
Patent number: 10683343Abstract: The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).Type: GrantFiled: May 14, 2018Date of Patent: June 16, 2020Assignee: ADMA BIOLOGICS, INC.Inventors: Adam S. Grossman, James Mond, Jerrold B. Grossman, Dov A. Goldstein
-
Patent number: 10259865Abstract: The present invention relates to compositions and methods for the treatment of infection caused by Streptococcus pneumonia. In particular, the invention provides human hyperimmune globulin and compositions thereof for preventing or treating pneumococcal infection. The invention provides methods of producing hyperimmune globulin containing high titers of opsonophagocytic anti-pneumococcal antibodies, compositions containing same, and methods of using the compositions for the prevention and treatment of pneumococcal infection. The invention further provides methods of preventing or treating pneumococcal infection (e.g., upper respiratory infections (e.g., bronchitis, otitis, sinusitis, etc.)) in immunocompromised subjects via administration of hyperimmune globulin compositions of the invention (e.g., containing a high titer of opsonophagocytic anti-pneumococcal antibodies) to immunocompromised subjects.Type: GrantFiled: March 15, 2017Date of Patent: April 16, 2019Assignee: ADMA Biologics, Inc.Inventors: James Mond, Adam S. Grossman
-
Patent number: 9969793Abstract: The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).Type: GrantFiled: November 13, 2017Date of Patent: May 15, 2018Assignee: ADMA Biologics, Inc.Inventors: Adam S. Grossman, James Mond, Jerrold B. Grossman, Dov A. Goldstein
-
Patent number: 9815886Abstract: The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).Type: GrantFiled: January 8, 2015Date of Patent: November 14, 2017Assignee: ADMA BIOLOGICS, INC.Inventors: Adam S. Grossman, James Mond, Jerrold B. Grossman, Dov A. Goldstein
-
Patent number: 9714283Abstract: The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).Type: GrantFiled: July 2, 2015Date of Patent: July 25, 2017Assignee: ADMA BIOLOGICS, INC.Inventors: Adam S. Grossman, Jerrold B. Grossman, James Mond, Dov A. Goldstein
-
Patent number: 9107906Abstract: The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).Type: GrantFiled: January 8, 2015Date of Patent: August 18, 2015Assignee: ADMA BIOLOGICS, INC.Inventors: Adam S. Grossman, James Mond, Jerrold B. Grossman