Abstract: The description relates to a system for assessing the functional performance of an individual, the system comprising a sensor device; a monitoring system, connectable to the sensor device, configured to receive signals coming from the sensor device, pre-process the signals received from the sensor device, extract the main features of the pre-processed signals to be used as predictor variables, assess the functional performance of an individual based on the predictor variables.
Type:
Grant
Filed:
December 19, 2019
Date of Patent:
February 20, 2024
Assignee:
ADMINISTRACIÓN GENERAL DE LA COMUNIDAD AUTÓNOMA DE EUSKADI
Inventors:
Jaime Herran Planchuelo, Larraitz Añorga Gomez, Itziar Vergara Micheltorena, Kalliopi Vrotsou, Marcos Jesus Arauzo Bravo, Ander Matheu Fernández
Abstract: The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.
Type:
Grant
Filed:
May 23, 2017
Date of Patent:
July 5, 2022
Assignees:
UNIVERSIDAD DEL PAIS VASCO, ADMINISTRACION GENERAL DE LA COMUNIDAD AUTONOMA DE EUSKADI
Inventors:
Ainara Vallejo Illarramendi, Adolfo Jose Lopez De Munain Arregi, Pablo Ferron Celma, Jesus Maria Aizpurua Iparraguirre, Aitziber Irastorza Epelde, Jose Ignacio Miranda Murua, Ivan Toral Ojeda, Garazi Aldanondo Aristizabal
Abstract: The present invention provides a method for detecting the presence or absence of a target analyte in a test sample, comprising the steps: i) providing a plurality of detector nanoparticles comprising a first detector nanoparticle functionalised with a first probe specific for a first region of a target analyte and a second detector nanoparticle functionalised with a second probe specific for a second region of said target analyte; and ii) contacting said detector nanoparticles with a test sample under conditions suitable for the binding of the specific probes to the target analyte, wherein target analyte-induced agglomeration of the detector nanoparticles permits the release of a detectable signal means from a signal reservoir. Also provided are related devices and systems for performing the method of the invention.
Type:
Application
Filed:
October 10, 2016
Publication date:
September 13, 2018
Applicants:
ADMINISTRACION GENERAL DE LA COMUNIDAD AUTONOMA DE EUSKADI, UNIVERSIDAD DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA, BASQUE CENTERCENTER FOR MACROMOLECULAR DESIGN AND ENGINEERING. POLYMAT FUNDAZIOA
Inventors:
Charles Henderson Lawrie, Lourdes Basabe-Desmonts, Thomas Schäfer, Luis Manuel Liz Marzán, Wolfgang Johann Parak
Abstract: The invention relates to an improved cranial device with a rotary inclination detector, including a container box which can be secured to the cranium of sleeping person and which contains an electric motor and an eccentric counterweight coupled thereto, forming a vibrator. The device also includes a battery or a battery holder for at least one battery, which is provided with two axially opposed projecting contacts or studs. The container box is provided with inclined formations with dielectric properties, on which the battery or battery holder can roll by means of the studs thereof, and two electric contacts on which the inclined formations terminate, such that, when the battery holder is placed on the electric contacts, the motor circuit is closed, thereby activating the vibrator.
Type:
Grant
Filed:
February 26, 2010
Date of Patent:
August 26, 2014
Assignees:
Sibel, S.A., Administracion General de la Comunidad Autonoma de Euskadi
Inventors:
Daniel Oreja Puerto, Jordi Rigau Rigau, Joaquin Jose Duran Cantolla