Patents Assigned to Administrative Center of New Drug Research, The State Pharmaceutical Administration of China
  • Tetrahydroprotoberberine quaternary ammonium compounds useful in for treating arrhythmia
    Patent number: 5470852
    Abstract: A tetrahydroprotoberberine quaternary ammonium compound represented by the formula: ##STR1## wherein R.sub.1, R.sub.2, R' and X are as defined in the specification. A method of preparing the compound is provided. The compounds can suppress arrhythmia and ventricular fibrillation, protect against myocardial ischemia, and can be conveniently orally administered.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: November 28, 1995
    Assignees: China Pharmaceutical University, Administrative Center of New Drug Research, The State Pharmaceutical Administration of China
    Inventors: Sixun Peng, Dezai Dai, Zhenya Huang, Wenlong Huang, Youqun Wang, Can Zhang, Feng Yu